Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KIM00_RS11065 Genome accession   NZ_CP074946
Coordinates   2216391..2217047 (+) Length   218 a.a.
NCBI ID   WP_219891808.1    Uniprot ID   -
Organism   Escherichia coli strain 05_3471     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2211391..2222047
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KIM00_RS11030 (KIM00_10930) dcyD 2212270..2213256 (+) 987 WP_001128238.1 D-cysteine desulfhydrase -
  KIM00_RS11035 (KIM00_10935) tcyL 2213271..2213939 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  KIM00_RS11040 (KIM00_10940) tcyN 2213936..2214688 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KIM00_RS11045 (KIM00_10945) sdiA 2214918..2215640 (+) 723 WP_001154265.1 transcriptional regulator SdiA -
  KIM00_RS11050 (KIM00_10950) yecF 2215708..2215932 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  KIM00_RS11055 (KIM00_10955) yecU 2215919..2216095 (-) 177 WP_001342215.1 protein YecU -
  KIM00_RS11060 - 2216133..2216249 (-) 117 WP_001302039.1 hypothetical protein -
  KIM00_RS11065 (KIM00_10960) letA 2216391..2217047 (+) 657 WP_219891808.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KIM00_RS11070 (KIM00_10965) uvrC 2217044..2218876 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  KIM00_RS11075 (KIM00_10970) pgsA 2218933..2219481 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KIM00_RS11095 (KIM00_10990) - 2220474..2220755 (+) 282 WP_001303543.1 hypothetical protein -
  KIM00_RS11100 (KIM00_10995) - 2220944..2221084 (-) 141 WP_000078921.1 Hok/Gef family protein -
  KIM00_RS11105 (KIM00_11000) - 2221275..2221535 (-) 261 WP_000488107.1 ogr/Delta-like zinc finger family protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23763.49 Da        Isoelectric Point: 6.6397

>NTDB_id=495929 KIM00_RS11065 WP_219891808.1 2216391..2217047(+) (letA) [Escherichia coli strain 05_3471]
MINVLLVDDHELVRAGIRGILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=495929 KIM00_RS11065 WP_219891808.1 2216391..2217047(+) (letA) [Escherichia coli strain 05_3471]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGAGGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.242

94.954

0.477
  letA Legionella pneumophila strain ERS1305867

50.242

94.954

0.477