Detailed information    

insolico Bioinformatically predicted

Overview

Name   hapR   Type   Regulator
Locus tag   INP70_RS10850 Genome accession   NZ_CP063420
Coordinates   2423427..2424038 (+) Length   203 a.a.
NCBI ID   WP_000340100.1    Uniprot ID   Q4F6W7
Organism   Vibrio cholerae strain VC_hf7     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2418427..2429038
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP70_RS10830 - 2418763..2419680 (-) 918 WP_000271066.1 ABC transporter ATP-binding protein -
  INP70_RS10835 - 2420061..2421707 (-) 1647 WP_000484912.1 SulP family inorganic anion transporter -
  INP70_RS10840 can 2421855..2422523 (+) 669 WP_001114117.1 carbonate dehydratase -
  INP70_RS10845 hpt 2422598..2423131 (-) 534 WP_000683351.1 hypoxanthine phosphoribosyltransferase -
  INP70_RS10850 hapR 2423427..2424038 (+) 612 WP_000340100.1 quorum-sensing master transcriptional regulator HapR Regulator
  INP70_RS10855 rsmI 2424248..2425114 (-) 867 WP_000131545.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  INP70_RS10860 - 2425184..2426989 (+) 1806 WP_001017154.1 penicillin-binding protein activator -
  INP70_RS10865 - 2426976..2427344 (+) 369 WP_001892065.1 YraN family protein -
  INP70_RS10870 - 2427348..2427938 (+) 591 WP_000887295.1 phosphoheptose isomerase -
  INP70_RS10875 - 2427941..2428510 (+) 570 WP_000836328.1 BON domain-containing protein -

Sequence

Protein


Download         Length: 203 a.a.        Molecular weight: 23720.44 Da        Isoelectric Point: 6.6356

>NTDB_id=495532 INP70_RS10850 WP_000340100.1 2423427..2424038(+) (hapR) [Vibrio cholerae strain VC_hf7]
MDASIEKRPRTRLSPQKRKLQLMEIALEVFAKRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDDVLNFVVRQYSNFL
TDHIDLDLDVKTNLQTLCKEMVKLAMTDCHWLKVWFEWSASTRDEVWPLFVSTNRTNQLLIRNMFMKAMERGELCEKHDV
DNMASLFHGIFYSIFLQVNRLGEQEAVYKLVDSYLNMLCIYKN

Nucleotide


Download         Length: 612 bp        

>NTDB_id=495532 INP70_RS10850 WP_000340100.1 2423427..2424038(+) (hapR) [Vibrio cholerae strain VC_hf7]
ATGGACGCATCAATCGAAAAACGCCCTCGAACTCGGCTATCGCCTCAAAAACGCAAACTACAACTGATGGAAATCGCGTT
GGAAGTGTTTGCTAAACGCGGCATTGGTCGTGGTGGTCACGCAGATATTGCCGAGATTGCGCAAGTCTCCGTTGCAACAG
TGTTCAACTACTTCCCAACTCGTGAAGACTTGGTTGACGATGTGCTGAATTTTGTGGTTCGTCAGTACTCCAACTTTTTG
ACCGATCACATCGATCTTGATTTGGATGTGAAAACCAACCTACAAACTCTGTGCAAAGAGATGGTGAAATTGGCGATGAC
CGATTGTCACTGGCTCAAAGTCTGGTTTGAGTGGAGTGCTTCAACCCGTGACGAAGTTTGGCCACTGTTTGTTTCCACCA
ACCGAACTAACCAACTGCTGATCAGAAACATGTTTATGAAAGCGATGGAACGTGGCGAATTGTGTGAGAAACACGATGTC
GATAACATGGCCAGCCTGTTCCACGGCATCTTCTACTCCATCTTCTTACAAGTGAACCGTTTAGGTGAACAAGAAGCAGT
GTATAAGCTGGTCGATAGCTACCTCAATATGCTGTGTATCTATAAGAACTAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, tetR family (TetR_N)

(23-67)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4F6W7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hapR Vibrio cholerae C6706

99.507

100

0.995
  hapR Vibrio cholerae strain A1552

99.507

100

0.995
  opaR Vibrio parahaemolyticus RIMD 2210633

72.727

97.537

0.709