Detailed information NTG0049542

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SPYALAB49_RS06080
• Genome accession: NC_017596
• Coordinates: 1199324..1200361 (-)
• Length: 345 a.a.
• NCBI ID: WP_011284961.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes Alab49
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1194324..1205361

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPYALAB49_RS06055 (SPYALAB49_001241)	-	1194328..1194855 (-)	528	WP_014635585.1	Dps family protein	-
SPYALAB49_RS06060 (SPYALAB49_001242)	-	1195083..1195709 (+)	627	WP_002989076.1	A24 family peptidase	-
SPYALAB49_RS06065 (SPYALAB49_001243)	rlmN	1195791..1196870 (-)	1080	WP_002992788.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
SPYALAB49_RS06070 (SPYALAB49_001244)	-	1196874..1197494 (-)	621	WP_002992791.1	YutD family protein	-
SPYALAB49_RS06075 (SPYALAB49_001246)	-	1197942..1198919 (-)	978	WP_002994809.1	LacI family DNA-binding transcriptional regulator	-
SPYALAB49_RS06080 (SPYALAB49_001247)	sepM	1199324..1200361 (-)	1038	WP_011284961.1	SepM family pheromone-processing serine protease	Regulator
SPYALAB49_RS06085 (SPYALAB49_001248)	coaD	1200348..1200839 (-)	492	WP_002983821.1	pantetheine-phosphate adenylyltransferase	-
SPYALAB49_RS06090 (SPYALAB49_001249)	rsmD	1200829..1201368 (-)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SPYALAB49_RS06095 (SPYALAB49_001250)	asnA	1201491..1202483 (-)	993	WP_002983817.1	aspartate--ammonia ligase	-
SPYALAB49_RS06100 (SPYALAB49_001251)	arcC	1202796..1203746 (-)	951	WP_010922501.1	carbamate kinase	-
SPYALAB49_RS06105 (SPYALAB49_001252)	-	1203766..1205097 (-)	1332	WP_011285641.1	dipeptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37571.27 Da
• Isoelectric Point: 9.6692

>NTDB_id=49542 SPYALAB49_RS06080 WP_011284961.1 1199324..1200361(-) (sepM) [Streptococcus pyogenes Alab49]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDTDFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=49542 SPYALAB49_RS06080 WP_011284961.1 1199324..1200361(-) (sepM) [Streptococcus pyogenes Alab49]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCGCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATACTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAG

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

• PDZ domain (PDZ_2) (129-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	68.986	100	0.69