Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KIM11_RS18340 Genome accession   NZ_CP074904
Coordinates   3507244..3507900 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 08_4358     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3502244..3512900
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KIM11_RS18310 (KIM11_18035) yecA 3503495..3504160 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  KIM11_RS18330 (KIM11_18055) pgsA 3504810..3505358 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KIM11_RS18335 (KIM11_18060) uvrC 3505415..3507247 (-) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  KIM11_RS18340 (KIM11_18065) letA 3507244..3507900 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KIM11_RS18345 - 3508042..3508158 (+) 117 WP_001302039.1 hypothetical protein -
  KIM11_RS18350 (KIM11_18070) yecU 3508196..3508372 (+) 177 WP_001342215.1 protein YecU -
  KIM11_RS18355 (KIM11_18075) yecF 3508359..3508583 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  KIM11_RS18360 (KIM11_18080) sdiA 3508651..3509373 (-) 723 WP_001154265.1 transcriptional regulator SdiA -
  KIM11_RS18365 (KIM11_18085) tcyN 3509603..3510355 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KIM11_RS18370 (KIM11_18090) tcyL 3510352..3511020 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  KIM11_RS18375 (KIM11_18095) dcyD 3511035..3512021 (-) 987 WP_001128246.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=495053 KIM11_RS18340 WP_000611328.1 3507244..3507900(-) (letA) [Escherichia coli strain 08_4358]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=495053 KIM11_RS18340 WP_000611328.1 3507244..3507900(-) (letA) [Escherichia coli strain 08_4358]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482