Detailed information NTG0494796

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: IPU21_RS04575
• Genome accession: NZ_CP063368
• Coordinates: 1015927..1016970 (+)
• Length: 347 a.a.
• NCBI ID: WP_096542451.1
• Uniprot ID: A0AAQ0D872
• Organism: Staphylococcus delphini strain 245-1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1010927..1021970

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IPU21_RS04555 (IPU21_04570)	-	1012873..1013871 (-)	999	WP_096542445.1	FUSC family protein	-
IPU21_RS04560 (IPU21_04575)	map	1013968..1014729 (+)	762	WP_019166460.1	type I methionyl aminopeptidase	-
IPU21_RS04565 (IPU21_04580)	-	1014827..1015216 (+)	390	WP_096542447.1	hypothetical protein	-
IPU21_RS04570 (IPU21_04585)	liaF	1015229..1015930 (+)	702	WP_096606284.1	cell wall-active antibiotics response protein LiaF	-
IPU21_RS04575 (IPU21_04590)	vraS	1015927..1016970 (+)	1044	WP_096542451.1	sensor histidine kinase	Regulator
IPU21_RS04580 (IPU21_04595)	vraR	1016960..1017589 (+)	630	WP_212575318.1	response regulator transcription factor	Regulator
IPU21_RS04585 (IPU21_04600)	-	1018229..1018810 (-)	582	WP_096597677.1	beta-class carbonic anhydrase	-
IPU21_RS04590 (IPU21_04605)	-	1018843..1020189 (-)	1347	WP_212575319.1	YihY/virulence factor BrkB family protein	-
IPU21_RS04595 (IPU21_04610)	-	1020405..1020692 (-)	288	WP_014613485.1	YtxH domain-containing protein	-
IPU21_RS04600 (IPU21_04615)	-	1020700..1021158 (-)	459	WP_019166466.1	low molecular weight protein-tyrosine-phosphatase	-
IPU21_RS04605 (IPU21_04620)	-	1021292..1021495 (+)	204	WP_019169369.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39895.19 Da
• Isoelectric Point: 5.0397

>NTDB_id=494796 IPU21_RS04575 WP_096542451.1 1015927..1016970(+) (vraS) [Staphylococcus delphini strain 245-1]
MNHYVRAIGSMLILVYSLLTAFFFIDKVFTNIIFFQGMFYTQILGIPVFIFLNLVVIFLCIIVGCVLAYKINQQNDWVKQ
QIVRAFEGETVGINDQQLELYNETIELYQALVPLNQELHKMRIKTQNLTNETYNLNDLKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETDLAPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKSLVTDLQRKVPIKVVQEI
DEFEVPKGIEDHLFRITQEAISNTLRHAEGTQVTVELLNRNDYLLLRIQDDGVGFNVDDKLEQSYGLKNMRERAIEIGAT
FHIVSLPDAGTRIEVKAPLEKEEQHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=494796 IPU21_RS04575 WP_096542451.1 1015927..1016970(+) (vraS) [Staphylococcus delphini strain 245-1]
ATGAATCACTACGTCCGAGCGATAGGTTCGATGCTCATTCTCGTATATAGTTTGCTCACTGCTTTTTTCTTTATCGATAA
AGTGTTTACCAATATCATTTTCTTTCAAGGGATGTTTTATACACAAATTTTAGGCATTCCCGTATTTATCTTTTTGAATT
TAGTCGTCATTTTTTTATGTATTATCGTGGGCTGTGTGTTAGCTTATAAAATCAATCAACAAAATGATTGGGTGAAGCAA
CAAATCGTTCGTGCTTTCGAAGGCGAAACAGTGGGAATCAATGATCAACAACTTGAGCTGTATAATGAAACGATTGAATT
GTACCAAGCGCTCGTCCCATTGAATCAAGAACTGCATAAAATGCGGATTAAAACACAAAATTTAACGAATGAAACGTATA
ATTTAAATGATTTGAAGGTGAAAAAGATTATAGAAGATGAACGGCAGCGTTTAGCACGAGAATTGCATGATAGTGTGTCG
CAACAACTTTTCGCGGCAAGTATGATGTTGTCTGCAATCAAGGAAACAGATTTAGCTCCACCGTTAGACCAACAAATTCC
AACGTTAGAAAAAATGGTGCAAGACTCACAACTTGAAATGCGTGCTCTGTTACTTCATTTGAGACCTATAGGATTGAAGG
ATAAATCGTTAGGTGAGGGGATAAAATCGCTTGTGACGGATTTACAACGCAAAGTGCCCATTAAAGTCGTGCAAGAAATT
GATGAGTTTGAAGTCCCTAAAGGTATTGAGGATCACCTTTTTAGGATTACCCAAGAAGCGATTTCCAATACGTTACGACA
TGCTGAGGGAACGCAAGTAACGGTAGAATTACTTAACCGCAATGATTATTTATTGTTGCGTATACAAGATGACGGCGTTG
GATTTAATGTCGATGATAAATTAGAACAAAGTTATGGATTAAAAAATATGCGTGAACGTGCAATAGAGATTGGTGCCACG
TTTCATATCGTCTCATTACCTGATGCAGGGACGAGAATAGAAGTGAAAGCACCACTTGAAAAGGAGGAACAGCATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-341)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	82.997	100	0.83