Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SSAL_RS08300 Genome accession   NC_017594
Coordinates   1791295..1792614 (-) Length   439 a.a.
NCBI ID   WP_014633573.1    Uniprot ID   -
Organism   Streptococcus salivarius 57.I     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1781891..1792614 1791295..1792614 within 0


Gene organization within MGE regions


Location: 1781891..1792614
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSAL_RS08225 (Ssal_01815) - 1781891..1782424 (+) 534 WP_002886644.1 DUF402 domain-containing protein -
  SSAL_RS08230 (Ssal_01816) - 1782454..1783113 (-) 660 WP_002886642.1 DUF1803 domain-containing protein -
  SSAL_RS08235 (Ssal_01817) - 1783168..1784100 (-) 933 WP_014633571.1 manganese-dependent inorganic pyrophosphatase -
  SSAL_RS08290 (Ssal_01821) raiA 1790025..1790573 (-) 549 WP_002883786.1 ribosome-associated translation inhibitor RaiA -
  SSAL_RS08295 (Ssal_01822) - 1790652..1791314 (-) 663 WP_045001926.1 ComF family protein -
  SSAL_RS08300 (Ssal_01823) comFA/cflA 1791295..1792614 (-) 1320 WP_014633573.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50678.78 Da        Isoelectric Point: 9.2419

>NTDB_id=49421 SSAL_RS08300 WP_014633573.1 1791295..1792614(-) (comFA/cflA) [Streptococcus salivarius 57.I]
MVPKEYYGRLFTKEQLPVDYHSEAFTLESMIKVDKQLRCKRCYSQIEEDWQLPEGQYYCRACIVFGRNQEGKELYYFPSK
TSEIEFPALKWLGELTPYQAEVSEKLLKTYQKQKDSLVHAVTGAGKTEMIYKIVAYVLESKGNVAIASPRVDVCRELFLR
MQRAFTCSISLFHAESEPYDGSPLVIATTHQLLKFYQNFDLVIVDEVDAFPFVGNVMLNHAVEQAKKETGRYIYLTATST
ISLEEQVRLGAIEKHHLARRFHGNPLVLPKFCWQGRLQKFLMRGKLPRPLLYQIKKQRKSKFPLLIFFPNIAIGEKFTSI
LQKYLPDEKMAFVSSKSEERSATVEQFREKELSILVTTTILERGVTFPQVDVFVCMANHHLYTSSSLIQIGGRVGRSPDR
PTGKLYFFHEGLSKSMLRCREEIKVMNKKGGFNNEVSTM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=49421 SSAL_RS08300 WP_014633573.1 1791295..1792614(-) (comFA/cflA) [Streptococcus salivarius 57.I]
ATGGTACCTAAAGAATATTATGGACGACTATTTACGAAAGAACAGTTGCCAGTGGACTATCACTCAGAGGCTTTTACATT
AGAAAGCATGATAAAGGTCGATAAACAACTTAGATGTAAAAGATGTTACAGTCAGATAGAGGAAGATTGGCAATTACCGG
AAGGTCAGTATTATTGCAGAGCGTGTATTGTCTTTGGCAGAAACCAAGAAGGAAAAGAACTTTATTATTTTCCTTCAAAA
ACATCTGAAATTGAATTTCCTGCTTTGAAGTGGTTGGGAGAACTGACGCCCTATCAAGCTGAGGTCTCAGAGAAGCTTTT
AAAAACATATCAAAAACAGAAAGACAGCCTCGTACATGCTGTGACCGGTGCTGGTAAGACCGAGATGATTTATAAAATCG
TTGCCTATGTTCTTGAAAGTAAAGGTAATGTAGCTATCGCAAGTCCTCGGGTTGATGTTTGTCGAGAGTTATTTCTACGT
ATGCAGAGGGCTTTTACTTGTAGTATTTCTCTGTTTCATGCTGAGAGTGAACCATATGATGGTAGTCCGCTTGTAATAGC
TACCACCCATCAATTACTAAAGTTTTACCAGAACTTTGACCTAGTTATCGTTGATGAGGTTGATGCATTCCCTTTTGTAG
GAAATGTCATGTTAAATCATGCTGTGGAGCAGGCAAAGAAAGAAACCGGTCGCTATATTTATTTAACAGCGACTTCTACA
ATATCTTTAGAAGAGCAAGTTCGACTTGGAGCTATAGAAAAACATCACCTTGCCAGACGTTTCCATGGAAATCCTTTAGT
ACTTCCTAAATTCTGCTGGCAAGGAAGATTACAAAAATTTCTAATGAGAGGCAAGCTTCCAAGACCCCTTCTTTATCAGA
TTAAAAAGCAACGTAAATCAAAGTTTCCTCTATTAATATTTTTCCCAAATATAGCGATAGGTGAAAAGTTTACTAGCATT
CTGCAAAAATATCTTCCAGATGAAAAAATGGCCTTTGTTTCTTCAAAAAGCGAGGAGCGTTCAGCTACCGTAGAGCAGTT
CCGGGAAAAAGAGTTATCCATCTTAGTGACAACAACTATCCTTGAACGTGGTGTAACCTTTCCACAAGTAGATGTTTTTG
TTTGTATGGCAAATCATCACTTATACACTAGTTCGAGTCTTATTCAGATAGGAGGTCGAGTTGGAAGATCCCCAGATAGA
CCGACAGGAAAGCTTTATTTCTTTCATGAAGGACTATCCAAATCTATGCTTCGTTGTCGAGAAGAAATAAAAGTTATGAA
TAAAAAAGGAGGATTTAACAATGAAGTGTCTACTATGTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-207)

Helicase conserved C-terminal domain (Helicase_C)

(290-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae TIGR4

55.452

98.178

0.544
  comFA/cflA Streptococcus pneumoniae Rx1

55.452

98.178

0.544
  comFA/cflA Streptococcus pneumoniae D39

55.452

98.178

0.544
  comFA/cflA Streptococcus pneumoniae R6

55.452

98.178

0.544
  comFA/cflA Streptococcus mitis NCTC 12261

54.608

98.861

0.54
  comFA/cflA Streptococcus mitis SK321

54.292

98.178

0.533
  comFA Lactococcus lactis subsp. cremoris KW2

45.368

95.9

0.435
  comFA Latilactobacillus sakei subsp. sakei 23K

38.073

99.317

0.378

Multiple sequence alignment