Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KIM27_RS16550 Genome accession   NZ_CP074849
Coordinates   3247889..3248545 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 7_12_15B     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3242889..3253545
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KIM27_RS16520 (KIM27_16310) yecA 3244140..3244805 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  KIM27_RS16540 (KIM27_16330) pgsA 3245455..3246003 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KIM27_RS16545 (KIM27_16335) uvrC 3246060..3247892 (-) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  KIM27_RS16550 (KIM27_16340) letA 3247889..3248545 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KIM27_RS16555 - 3248687..3248803 (+) 117 WP_001302039.1 hypothetical protein -
  KIM27_RS16560 (KIM27_16345) yecU 3248841..3249017 (+) 177 WP_001342215.1 protein YecU -
  KIM27_RS16565 (KIM27_16350) yecF 3249004..3249228 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  KIM27_RS16570 (KIM27_16355) sdiA 3249296..3250018 (-) 723 WP_001154265.1 transcriptional regulator SdiA -
  KIM27_RS16575 (KIM27_16360) tcyN 3250248..3251000 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KIM27_RS16580 (KIM27_16365) tcyL 3250997..3251665 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  KIM27_RS16585 (KIM27_16370) dcyD 3251680..3252666 (-) 987 WP_001128238.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=493702 KIM27_RS16550 WP_000611328.1 3247889..3248545(-) (letA) [Escherichia coli strain 7_12_15B]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=493702 KIM27_RS16550 WP_000611328.1 3247889..3248545(-) (letA) [Escherichia coli strain 7_12_15B]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482