Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE1/comEA   Type   Machinery gene
Locus tag   INP94_RS01440 Genome accession   NZ_CP063120
Coordinates   293764..294129 (-) Length   121 a.a.
NCBI ID   WP_197543804.1    Uniprot ID   A0A7M1NY46
Organism   Haemophilus parainfluenzae strain M1C137_2     
Function   dsDNA binding (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 288764..299129
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INP94_RS01420 (INP94_01420) - 288901..289404 (-) 504 WP_197543800.1 surface-adhesin E family protein -
  INP94_RS01425 (INP94_01425) pflA 289459..290199 (-) 741 WP_197543801.1 pyruvate formate lyase 1-activating protein -
  INP94_RS01430 (INP94_01430) pflB 290329..292641 (-) 2313 WP_197543802.1 formate C-acetyltransferase -
  INP94_RS01435 (INP94_01435) focA 292697..293551 (-) 855 WP_197543803.1 formate transporter FocA -
  INP94_RS01440 (INP94_01440) comE1/comEA 293764..294129 (-) 366 WP_197543804.1 helix-hairpin-helix domain-containing protein Machinery gene
  INP94_RS01445 (INP94_01445) - 294275..294592 (-) 318 WP_005695251.1 heavy metal-binding domain-containing protein -
  INP94_RS01450 (INP94_01450) rdgB 294631..295230 (-) 600 WP_178410614.1 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase -
  INP94_RS01455 (INP94_01455) - 295361..295732 (+) 372 WP_070868331.1 DUF305 domain-containing protein -
  INP94_RS01460 (INP94_01460) ispH 295779..296723 (-) 945 WP_197543805.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase -
  INP94_RS01465 (INP94_01465) lspA 296720..297211 (-) 492 WP_005695245.1 signal peptidase II -
  INP94_RS01470 (INP94_01470) glmU 297328..298698 (-) 1371 WP_049371771.1 bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU -

Sequence

Protein


Download         Length: 121 a.a.        Molecular weight: 13248.26 Da        Isoelectric Point: 9.6909

>NTDB_id=493068 INP94_RS01440 WP_197543804.1 293764..294129(-) (comE1/comEA) [Haemophilus parainfluenzae strain M1C137_2]
MKLLMKQLFSSLFIAGAMLSTQALAEEKTAEQAQPQMQVQQQTAVQAPSQTVQQTVSDKLNINTASASEIQKALIGIGAK
KAEAIVQYREKHGNFTMAEQLLEVQGIGKATLEKNRDRIAF

Nucleotide


Download         Length: 366 bp        

>NTDB_id=493068 INP94_RS01440 WP_197543804.1 293764..294129(-) (comE1/comEA) [Haemophilus parainfluenzae strain M1C137_2]
ATGAAATTATTGATGAAACAGTTATTTAGTTCATTATTTATTGCAGGCGCGATGTTGAGCACACAAGCGCTTGCAGAAGA
AAAGACAGCTGAGCAGGCTCAACCGCAAATGCAAGTGCAGCAACAAACTGCTGTACAAGCACCATCACAAACTGTACAAC
AAACGGTGAGTGATAAATTAAATATCAATACCGCCAGTGCATCAGAAATTCAAAAAGCACTAATTGGTATTGGTGCGAAA
AAGGCGGAAGCCATTGTGCAGTATCGTGAAAAGCACGGTAATTTTACTATGGCAGAGCAATTGCTTGAAGTACAAGGCAT
TGGTAAAGCAACGTTAGAGAAAAATCGCGATCGTATTGCGTTTTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(58-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7M1NY46

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE1/comEA Haemophilus influenzae Rd KW20

64.957

96.694

0.628
  comEA/comE1 Glaesserella parasuis strain SC1401

52.101

98.347

0.512