Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SPNINV200_RS01800 Genome accession   NC_017593
Coordinates   342988..343677 (+) Length   229 a.a.
NCBI ID   WP_000518018.1    Uniprot ID   -
Organism   Streptococcus pneumoniae INV200     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 337988..348677
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPNINV200_RS01775 (SPNINV200_03330) gpsB 338097..338426 (+) 330 WP_000146522.1 cell division regulator GpsB -
  SPNINV200_RS01785 (SPNINV200_03340) - 338912..340069 (+) 1158 WP_000711402.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  SPNINV200_RS01790 (SPNINV200_03350) mapZ 340082..341476 (+) 1395 WP_000039289.1 cell division site-positioning protein MapZ -
  SPNINV200_RS01795 (SPNINV200_03360) gndA 341552..342976 (+) 1425 WP_000158786.1 NADP-dependent phosphogluconate dehydrogenase -
  SPNINV200_RS01800 (SPNINV200_03370) covR 342988..343677 (+) 690 WP_000518018.1 response regulator transcription factor Regulator
  SPNINV200_RS01805 (SPNINV200_03380) cbpC 343775..344797 (+) 1023 WP_000771112.1 choline-binding protein CbpC -
  SPNINV200_RS01810 (SPNINV200_03390) cbpJ 344816..345814 (+) 999 WP_000771130.1 choline-binding protein CbpJ -
  SPNINV200_RS01815 (SPNINV200_03400) - 345932..347164 (-) 1233 WP_000765688.1 MFS transporter -
  SPNINV200_RS01820 (SPNINV200_03410) - 347207..348082 (-) 876 WP_014632445.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26898.22 Da        Isoelectric Point: 6.9836

>NTDB_id=49301 SPNINV200_RS01800 WP_000518018.1 342988..343677(+) (covR) [Streptococcus pneumoniae INV200]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=49301 SPNINV200_RS01800 WP_000518018.1 342988..343677(+) (covR) [Streptococcus pneumoniae INV200]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATTTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment