Detailed information NTG0049263

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SPNOXC_RS09465
• Genome accession: NC_017592
• Coordinates: 1756271..1757308 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727279.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae OXC141
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1751271..1762308

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPNOXC_RS09445 (SPNOXC17220)	-	1752010..1753341 (-)	1332	WP_000390039.1	hemolysin family protein	-
SPNOXC_RS09450 (SPNOXC17230)	endA	1753632..1754456 (-)	825	WP_001036786.1	DNA-entry nuclease EndA	Machinery gene
SPNOXC_RS09455 (SPNOXC17240)	-	1754495..1754683 (-)	189	WP_014632430.1	DNA-directed RNA polymerase subunit beta	-
SPNOXC_RS09460 (SPNOXC17250)	murA	1754676..1755959 (-)	1284	WP_000358034.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
SPNOXC_RS11990 (SPNOXC17260)	-	1755983..1756213 (-)	231	WP_001809307.1	DUF1146 family protein	-
SPNOXC_RS09465 (SPNOXC17270)	sepM	1756271..1757308 (-)	1038	WP_000727279.1	SepM family pheromone-processing serine protease	Regulator
SPNOXC_RS09470 (SPNOXC17280)	coaD	1757292..1757780 (-)	489	WP_001280736.1	pantetheine-phosphate adenylyltransferase	-
SPNOXC_RS09475 (SPNOXC17290)	rsmD	1757770..1758309 (-)	540	WP_000706951.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SPNOXC_RS09480 (SPNOXC17300)	asnA	1758374..1759366 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
SPNOXC_RS09490 (SPNOXC17310)	-	1759478..1760161 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
SPNOXC_RS09495 (SPNOXC17320)	-	1760217..1760957 (-)	741	WP_000152680.1	RNA methyltransferase	-
SPNOXC_RS09500 (SPNOXC17330)	-	1760991..1761269 (+)	279	WP_001174613.1	acylphosphatase	-
SPNOXC_RS09505 (SPNOXC17340)	yidC	1761347..1762273 (+)	927	WP_000835949.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37565.63 Da
• Isoelectric Point: 5.0724

>NTDB_id=49263 SPNOXC_RS09465 WP_000727279.1 1756271..1757308(-) (sepM) [Streptococcus pneumoniae OXC141]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDVKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=49263 SPNOXC_RS09465 WP_000727279.1 1756271..1757308(-) (sepM) [Streptococcus pneumoniae OXC141]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCACAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACGGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGAAAAAATGGGATTGGAATCGGCTTGATTGATCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGTGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (231-298)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588