Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   SPNOXC_RS09450 Genome accession   NC_017592
Coordinates   1753632..1754456 (-) Length   274 a.a.
NCBI ID   WP_001036786.1    Uniprot ID   A0A0B7LDF1
Organism   Streptococcus pneumoniae OXC141     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1748632..1759456
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPNOXC_RS09445 (SPNOXC17220) - 1752010..1753341 (-) 1332 WP_000390039.1 hemolysin family protein -
  SPNOXC_RS09450 (SPNOXC17230) endA 1753632..1754456 (-) 825 WP_001036786.1 DNA-entry nuclease EndA Machinery gene
  SPNOXC_RS09455 (SPNOXC17240) - 1754495..1754683 (-) 189 WP_014632430.1 DNA-directed RNA polymerase subunit beta -
  SPNOXC_RS09460 (SPNOXC17250) murA 1754676..1755959 (-) 1284 WP_000358034.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  SPNOXC_RS11990 (SPNOXC17260) - 1755983..1756213 (-) 231 WP_001809307.1 DUF1146 family protein -
  SPNOXC_RS09465 (SPNOXC17270) sepM 1756271..1757308 (-) 1038 WP_000727279.1 SepM family pheromone-processing serine protease Regulator
  SPNOXC_RS09470 (SPNOXC17280) coaD 1757292..1757780 (-) 489 WP_001280736.1 pantetheine-phosphate adenylyltransferase -
  SPNOXC_RS09475 (SPNOXC17290) rsmD 1757770..1758309 (-) 540 WP_000706951.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  SPNOXC_RS09480 (SPNOXC17300) asnA 1758374..1759366 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29921.59 Da        Isoelectric Point: 10.1197

>NTDB_id=49262 SPNOXC_RS09450 WP_001036786.1 1753632..1754456(-) (endA) [Streptococcus pneumoniae OXC141]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=49262 SPNOXC_RS09450 WP_001036786.1 1753632..1754456(-) (endA) [Streptococcus pneumoniae OXC141]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGGCACCTAATAGTCCCAAAACCAATCTTAGTCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7LDF1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

99.635

100

0.996
  endA Streptococcus pneumoniae D39

99.635

100

0.996
  endA Streptococcus pneumoniae R6

99.635

100

0.996
  endA Streptococcus pneumoniae TIGR4

99.635

100

0.996

Multiple sequence alignment