Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   INV104_RS14160 Genome accession   NC_017591
Coordinates   1982230..1982424 (-) Length   64 a.a.
NCBI ID   WP_001844285.1    Uniprot ID   -
Organism   Streptococcus pneumoniae INV104     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1977230..1987424
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INV104_RS10545 (INV104_17960) - 1977288..1978163 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  INV104_RS10550 (INV104_17970) pstC 1978281..1979144 (+) 864 WP_000165893.1 phosphate ABC transporter permease subunit PstC -
  INV104_RS10555 (INV104_17980) pstA 1979137..1979952 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  INV104_RS10560 (INV104_17990) pstB 1979954..1980706 (+) 753 WP_000536450.1 phosphate ABC transporter ATP-binding protein PstB -
  INV104_RS10565 (INV104_18000) phoU 1980721..1981371 (+) 651 WP_001245781.1 phosphate signaling complex protein PhoU -
  INV104_RS10570 (INV104_18010) - 1981412..1981864 (+) 453 Protein_1996 transposase -
  INV104_RS14155 - 1981979..1982230 (-) 252 WP_001844284.1 hypothetical protein -
  INV104_RS14160 comR 1982230..1982424 (-) 195 WP_001844285.1 helix-turn-helix domain-containing protein Regulator
  INV104_RS10580 (INV104_18030) - 1982636..1983652 (+) 1017 WP_000415116.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  INV104_RS10585 (INV104_18040) galU 1983674..1984573 (+) 900 WP_000202235.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  INV104_RS10590 (INV104_18050) - 1984645..1985322 (-) 678 WP_000658498.1 rhomboid family intramembrane serine protease -
  INV104_RS10595 (INV104_18060) - 1985306..1985845 (-) 540 WP_000834303.1 5-formyltetrahydrofolate cyclo-ligase -
  INV104_RS10600 (INV104_18070) - 1985857..1986987 (-) 1131 WP_000885071.1 N-acetyldiaminopimelate deacetylase -

Sequence

Protein


Download         Length: 64 a.a.        Molecular weight: 7337.58 Da        Isoelectric Point: 10.6965

>NTDB_id=49213 INV104_RS14160 WP_001844285.1 1982230..1982424(-) (comR) [Streptococcus pneumoniae INV104]
MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRPTLTKLKYIAERLGGGVKITS

Nucleotide


Download         Length: 195 bp        

>NTDB_id=49213 INV104_RS14160 WP_001844285.1 1982230..1982424(-) (comR) [Streptococcus pneumoniae INV104]
TTGCGAGAGTTTGGCGAAAAAATTAAAAGATTACGTTTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTC
TGAATTAAGTATCCGTCAATTAATTAGAATTGAAAATGGAGAATCCAGACCAACACTAACAAAGTTAAAATATATCGCTG
AACGTTTGGGGGGGGGGGTGAAGATTACAAGTTGA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(8-57)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS315

56.667

93.75

0.531
  comR Streptococcus pyogenes MGAS8232

56.667

93.75

0.531
  comR Streptococcus mutans UA159

57.895

89.063

0.516
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

61.111

84.375

0.516
  comR Streptococcus suis P1/7

52.542

92.188

0.484
  comR Streptococcus suis 05ZYH33

52.542

92.188

0.484
  comR Streptococcus suis D9

52.542

92.188

0.484
  comR Streptococcus salivarius SK126

53.571

87.5

0.469
  comR Streptococcus salivarius strain HSISS4

53.571

87.5

0.469
  comR Streptococcus thermophilus LMG 18311

51.786

87.5

0.453
  comR Streptococcus thermophilus LMD-9

51.786

87.5

0.453
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

61.702

73.438

0.453
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

50.877

89.063

0.453

Multiple sequence alignment