Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KHZ70_RS07825 Genome accession   NZ_CP074576
Coordinates   1645890..1646546 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain CS18F     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1640890..1651546
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KHZ70_RS07795 (KHZ70_07800) dcyD 1641770..1642756 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  KHZ70_RS07800 (KHZ70_07805) tcyL 1642771..1643439 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  KHZ70_RS07805 (KHZ70_07810) tcyN 1643436..1644188 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KHZ70_RS07810 (KHZ70_07815) sdiA 1644418..1645140 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  KHZ70_RS07815 (KHZ70_07820) yecF 1645207..1645431 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  KHZ70_RS07820 (KHZ70_07825) yecU 1645418..1645594 (-) 177 WP_000590344.1 protein YecU -
  KHZ70_RS25260 - 1645632..1645748 (-) 117 WP_001302039.1 hypothetical protein -
  KHZ70_RS07825 (KHZ70_07830) letA 1645890..1646546 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KHZ70_RS07830 (KHZ70_07835) uvrC 1646543..1648375 (+) 1833 WP_001283427.1 excinuclease ABC subunit UvrC Machinery gene
  KHZ70_RS07835 (KHZ70_07840) pgsA 1648432..1648980 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KHZ70_RS07855 (KHZ70_07860) yecA 1649630..1650295 (+) 666 WP_000847885.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=491612 KHZ70_RS07825 WP_000611335.1 1645890..1646546(+) (letA) [Escherichia coli strain CS18F]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=491612 KHZ70_RS07825 WP_000611335.1 1645890..1646546(+) (letA) [Escherichia coli strain CS18F]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486