Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KG092_RS09410 Genome accession   NZ_CP074366
Coordinates   1964258..1964914 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain ZYB62     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1959258..1969914
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KG092_RS09380 (KG092_09295) dcyD 1960138..1961124 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  KG092_RS09385 (KG092_09300) tcyL 1961139..1961807 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  KG092_RS09390 (KG092_09305) tcyN 1961804..1962556 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KG092_RS09395 (KG092_09310) sdiA 1962786..1963508 (+) 723 WP_001154268.1 transcriptional regulator SdiA -
  KG092_RS09400 (KG092_09315) yecF 1963575..1963799 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  KG092_RS09405 (KG092_09320) yecU 1963786..1963962 (-) 177 WP_001307856.1 protein YecU -
  KG092_RS25485 - 1964045..1964116 (-) 72 Protein_1835 transcriptional regulator -
  KG092_RS09410 (KG092_09325) letA 1964258..1964914 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KG092_RS09415 (KG092_09330) uvrC 1964911..1966743 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  KG092_RS09420 (KG092_09335) pgsA 1966800..1967348 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KG092_RS09440 (KG092_09355) - 1968044..1968784 (-) 741 WP_000440336.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=491011 KG092_RS09410 WP_000611335.1 1964258..1964914(+) (letA) [Escherichia coli strain ZYB62]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=491011 KG092_RS09410 WP_000611335.1 1964258..1964914(+) (letA) [Escherichia coli strain ZYB62]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486