Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KFQ11_RS09425 Genome accession   NZ_CP074354
Coordinates   1895071..1895727 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain XJ5.2     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1890071..1900727
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KFQ11_RS09395 (KFQ11_09315) dcyD 1890950..1891936 (+) 987 WP_001724631.1 D-cysteine desulfhydrase -
  KFQ11_RS09400 (KFQ11_09320) tcyL 1891951..1892619 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  KFQ11_RS09405 (KFQ11_09325) tcyN 1892616..1893368 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KFQ11_RS09410 (KFQ11_09330) sdiA 1893598..1894320 (+) 723 WP_001154258.1 transcriptional regulator SdiA -
  KFQ11_RS09415 (KFQ11_09335) yecF 1894388..1894612 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  KFQ11_RS09420 (KFQ11_09340) yecU 1894599..1894775 (-) 177 WP_001302050.1 protein YecU -
  KFQ11_RS23920 - 1894813..1894929 (-) 117 WP_089601844.1 transcriptional regulator -
  KFQ11_RS09425 (KFQ11_09345) letA 1895071..1895727 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KFQ11_RS09430 (KFQ11_09350) uvrC 1895724..1897556 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  KFQ11_RS09435 (KFQ11_09355) pgsA 1897613..1898161 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KFQ11_RS09455 (KFQ11_09375) yecA 1898810..1899475 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=490775 KFQ11_RS09425 WP_000611335.1 1895071..1895727(+) (letA) [Escherichia coli strain XJ5.2]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=490775 KFQ11_RS09425 WP_000611335.1 1895071..1895727(+) (letA) [Escherichia coli strain XJ5.2]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTTGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
AATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486