Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KGQ53_RS01305 Genome accession   NZ_CP074120
Coordinates   269777..270433 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain EC16     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 264777..275433
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KGQ53_RS01275 dcyD 265656..266642 (+) 987 WP_039023114.1 D-cysteine desulfhydrase -
  KGQ53_RS01280 tcyL 266657..267325 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  KGQ53_RS01285 tcyN 267322..268074 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KGQ53_RS01290 sdiA 268304..269026 (+) 723 WP_001154260.1 transcriptional regulator SdiA -
  KGQ53_RS01295 yecF 269094..269318 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  KGQ53_RS01300 yecU 269305..269481 (-) 177 WP_000590344.1 protein YecU -
  KGQ53_RS26205 - 269519..269635 (-) 117 WP_001302039.1 hypothetical protein -
  KGQ53_RS01305 letA 269777..270433 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KGQ53_RS01310 uvrC 270430..272262 (+) 1833 WP_212639636.1 excinuclease ABC subunit UvrC Machinery gene
  KGQ53_RS01315 pgsA 272319..272867 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KGQ53_RS01335 yecA 273516..274181 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=490662 KGQ53_RS01305 WP_000611328.1 269777..270433(+) (letA) [Escherichia coli strain EC16]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=490662 KGQ53_RS01305 WP_000611328.1 269777..270433(+) (letA) [Escherichia coli strain EC16]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482