Detailed information NTG0490618

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: KE639_RS20390
• Genome accession: NZ_CP074111
• Coordinates: 4409545..4410669 (-)
• Length: 374 a.a.
• NCBI ID: WP_030404779.1
• Uniprot ID: A0A6B3QRH4
• Organism: Streptomyces sp. V17-9
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4404545..4415669

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KE639_RS20365 (KE639_04067)	cseB	4405266..4405970 (-)	705	WP_165287730.1	two-component system response regulator CseB	-
KE639_RS20370 (KE639_04068)	-	4406094..4406771 (-)	678	WP_176154385.1	hypothetical protein	-
KE639_RS20375 (KE639_04069)	-	4406759..4407292 (-)	534	WP_003975479.1	SigE family RNA polymerase sigma factor	-
KE639_RS20380 (KE639_04070)	-	4407591..4408517 (-)	927	WP_125629511.1	A/G-specific adenine glycosylase	-
KE639_RS20385 (KE639_04071)	-	4408676..4409524 (+)	849	WP_212730806.1	hypothetical protein	-
KE639_RS20390 (KE639_04072)	disA	4409545..4410669 (-)	1125	WP_030404779.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
KE639_RS20395 (KE639_04073)	radA/sms	4410751..4412160 (-)	1410	WP_102932190.1	DNA repair protein RadA	Machinery gene
KE639_RS20400 (KE639_04074)	-	4412778..4414544 (+)	1767	WP_212730807.1	hypothetical protein	-
KE639_RS20405 (KE639_04075)	-	4414849..4415661 (-)	813	WP_212730808.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40084.82 Da
• Isoelectric Point: 5.0058

>NTDB_id=490618 KE639_RS20390 WP_030404779.1 4409545..4410669(-) (disA) [Streptomyces sp. V17-9]
MAANDRAAAPGKSGGSAGADGLMRASLSAVAPGTSLRDGLERVLRGNTGGLIVLGSDKTVEQMCTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQLLPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALAELDKLSHAELLELSTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=490618 KE639_RS20390 WP_030404779.1 4409545..4410669(-) (disA) [Streptomyces sp. V17-9]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGTGCCGGTGCCGATGGCCTGATGCGCGCCTCACT
GAGCGCCGTGGCGCCCGGCACGTCCCTGCGCGACGGCCTGGAGCGGGTCCTGCGCGGCAACACCGGCGGTCTGATCGTGC
TGGGCTCCGACAAGACCGTCGAGCAGATGTGCACGGGCGGTTTCGTGCTGGACGTCGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTGCTGTCGTCCGACCTGTCGAAGATCCTGCGGGCCGGGGTGCAGCTCCTTCC
GGATCCCACCATTCCGACGGAGGAGACCGGTACGCGGCACCGGACCGCCGACCGGGTCAGCAAGCAGGTCGGCTTCCCCG
TGGTGTCGGTTTCGCAGTCGATGCGGCTGATCGCCCTGTACGTGGACGGGCAGCGGCGGGTGCTGGAGGACTCGGCGGCG
ATCCTGTCGCGGGCCAATCAGGCACTGGCGACGCTGGAGCGGTACAAGCTGCGCCTCGACGAGGTCGCGGGCACGCTGTC
GGCGCTGGAGATCGAGGACCTGGTGACGGTGCGGGACGTCTCCGCGGTCGCGCAGCGGCTGGAGATGGTCCGCCGGATCG
CCACCGAGATCGCCGAGTACGTGGTGGAGCTGGGCACGGACGGGCGGCTGCTCGCGCTGCAGTTGGACGAGCTGATCGCC
GGGGTGGAGCCCGAACGCGAGCTGGTCGTGCGGGACTACGTACCGGAGCCGACCGCCAAGCGGTCCCGTACGGTCGACGA
GGCGCTCGCCGAGCTGGACAAGCTCAGCCACGCGGAACTGCTGGAACTGTCGACCGTGGCCCGGGCCCTGGGCTACACCG
GGTCGCCCGAGACGCTGGACTCGGCGGTGTCGCCGCGCGGCTTCCGGCTGCTGGCCAAGGTGCCGCGGCTGCCCGGCGCG
ATCATCGACCGGCTGGTGGAGCACTTCGGCGGTCTGCAGAAGCTGCTCGCCGCCAGTGTCGACGACCTGCAGACCGTGGA
CGGCGTCGGCGAGGCGCGGGCGCGCAGCGTGCGCGAGGGGCTGTCGCGGCTGGCGGAGTCGTCGATCCTGGAGCGCTACG
TCTGA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

3D structure

• AlphaFold DB: A0A6B3QRH4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	46.26	96.524	0.447