Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   SESEC_RS07080 Genome accession   NC_017582
Coordinates   1492647..1493999 (-) Length   450 a.a.
NCBI ID   WP_014623188.1    Uniprot ID   A0A6M1KZW6
Organism   Streptococcus equi subsp. zooepidemicus ATCC 35246     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1487647..1498999
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SESEC_RS07060 (SeseC_01786) rnc 1488468..1489160 (-) 693 WP_038674782.1 ribonuclease III -
  SESEC_RS07065 (SeseC_01790) - 1489419..1490933 (-) 1515 WP_014623184.1 helix-turn-helix domain-containing protein -
  SESEC_RS07075 (SeseC_01793) vicX 1491834..1492643 (-) 810 WP_014623187.1 MBL fold metallo-hydrolase Regulator
  SESEC_RS07080 (SeseC_01794) vicK 1492647..1493999 (-) 1353 WP_014623188.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SESEC_RS07085 (SeseC_01795) vicR 1493992..1494702 (-) 711 WP_012515994.1 response regulator YycF Regulator
  SESEC_RS07090 (SeseC_01796) - 1494911..1495927 (-) 1017 WP_014623189.1 DUF3114 domain-containing protein -
  SESEC_RS07095 (SeseC_01799) - 1495973..1497235 (-) 1263 WP_014623190.1 AMP-binding protein -
  SESEC_RS07100 (SeseC_01800) - 1497225..1498340 (-) 1116 WP_014623191.1 acetyl-CoA C-acyltransferase -
  SESEC_RS07105 (SeseC_01801) - 1498337..1498876 (-) 540 WP_014623192.1 hypothetical protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51527.91 Da        Isoelectric Point: 5.5557

>NTDB_id=49060 SESEC_RS07080 WP_014623188.1 1492647..1493999(-) (vicK) [Streptococcus equi subsp. zooepidemicus ATCC 35246]
MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLMSHKIRDLINGRYTDTINEKADIELMELSEQLNDLSD
VFRLTHENLAQEKNRLASILAYMTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVTQLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITS
IWLEIDNDKMTQVIENILNNAIKYSPDGGKIVVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=49060 SESEC_RS07080 WP_014623188.1 1492647..1493999(-) (vicK) [Streptococcus equi subsp. zooepidemicus ATCC 35246]
ATGACTAAGGACATCATTGGAAACCTTTCTGCATTTGAGCTAGCCATACTCTTATTGCTTGTTTTTGTTGCTTTTTATTT
CATTCATTTAGCCATTCGTGATTATCGCAATGCTCGGATCATTCGTCTGATGAGCCATAAGATAAGAGATTTGATCAATG
GTCGCTATACTGATACGATCAATGAAAAGGCTGATATTGAATTGATGGAGCTGTCTGAGCAGCTCAACGACCTATCAGAT
GTTTTTCGTCTGACCCATGAAAACCTTGCCCAAGAGAAAAATCGTCTTGCTAGTATTTTGGCTTATATGACAGATGGGGT
CCTTGCGACCAATCGTTCCGGCAAGATTATCATGATTAATGAGACTGCTCAAAAGCAGCTCAATTTAAATCGTGAGCAGG
CGCTGGAAAAAAACATTACAGATTTATTAGACAGTGACTCACCTTACACCTACCGAGAGCTGGTCTCAAAAACACCGATT
GTGACCTTAAATCGTCGTAATGACACAGGAGAGTTTGTTTCGCTGCGGCTGCGTTTTGCGCTTAATAGGCGAGAGAGCGG
CTTTATTTCAGGTCTAGTTGTTGTGCTTCATGACACGACTGAGCAGGAAAAGGAGGAGCGTGAGCGCAGACTCTTTGTCT
CAAATGTTAGCCATGAGCTTCGCACACCTTTGACCTCTGTCAAGTCATACCTAGAGGCTCTAGATGAGGGCGCGCTAAAG
GAGGACATAGCCCCAAGCTTTATAAAGGTCTCACTAGACGAAACCAATCGCATGATGCGCATGATTTCAGATTTGCTCAA
TCTATCAAGAATTGATAATCATGTGACACAGCTGTCTGTTGAAATGACCAACTTTACAGCCTTTATGACCTCTATCTTAA
ACCGCTTTGATTTGGTGAAAAATCAGCACACAAGCACAGGAAAATCCTATGAAATTGTCAGAGATTACCCTATTACCTCT
ATTTGGCTAGAAATTGACAATGACAAAATGACGCAGGTTATCGAAAATATTTTAAACAATGCAATCAAATATTCACCCGA
TGGCGGAAAAATTGTCGTCAACATGAAAACAACAGATACCCAGCTAATCATTTCGATTTCTGATGAGGGCTTGGGCATTC
CAAAAAAGGACCTGCCTTTGATTTTTGACCGTTTTTACCGAGTGGATAAGGCTAGGAGTAGAGCTCAAGGAGGGACCGGC
TTAGGGCTGGCTATTGCTAAAGAAATTATCAAGCAGCATCGAGGCTTTATTTGGGCCAAGAGCGATTATGGCAAGGGCTC
AACCTTTACCATTGTGTTACCTTACGAAAAGGATGCTGCTATCTATGATGAATGGGAGGATGATATTGATTAA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6M1KZW6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92

0.678
  micB Streptococcus pneumoniae Cp1015

66.824

94.444

0.631

Multiple sequence alignment