Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   ILP78_RS12235 Genome accession   NZ_CP062465
Coordinates   2450877..2451446 (-) Length   189 a.a.
NCBI ID   WP_000872881.1    Uniprot ID   -
Organism   Staphylococcus aureus strain MRSA - AMRF 6     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2445877..2456446
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ILP78_RS12195 (ILP78_12195) - 2446351..2446959 (-) 609 WP_000020306.1 class I SAM-dependent methyltransferase -
  ILP78_RS12200 (ILP78_12200) rplL 2447134..2447502 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  ILP78_RS12205 (ILP78_12205) rplJ 2447545..2448045 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  ILP78_RS12210 (ILP78_12210) rplA 2448317..2449009 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  ILP78_RS12215 (ILP78_12215) rplK 2449217..2449639 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  ILP78_RS12220 (ILP78_12220) nusG 2449820..2450368 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  ILP78_RS12225 (ILP78_12225) secE 2450381..2450563 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  ILP78_RS12230 (ILP78_12230) rpmG 2450619..2450762 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  ILP78_RS12235 (ILP78_12235) sigH 2450877..2451446 (-) 570 WP_000872881.1 sigma-70 family RNA polymerase sigma factor Regulator
  ILP78_RS12240 (ILP78_12240) - 2451527..2452051 (-) 525 WP_000664732.1 NYN domain-containing protein -
  ILP78_RS12245 (ILP78_12245) rlmB 2452051..2452797 (-) 747 WP_000390329.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  ILP78_RS12250 (ILP78_12250) - 2452805..2453209 (-) 405 WP_000370185.1 Mini-ribonuclease 3 -
  ILP78_RS12255 (ILP78_12255) cysS 2453202..2454602 (-) 1401 WP_000631966.1 cysteine--tRNA ligase -
  ILP78_RS12260 (ILP78_12260) cysE 2454586..2455233 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23096.97 Da        Isoelectric Point: 9.6924

>NTDB_id=490219 ILP78_RS12235 WP_000872881.1 2450877..2451446(-) (sigH) [Staphylococcus aureus strain MRSA - AMRF 6]
MKYDLTTQDSTIKRNNAINDKDFEKLVMNLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=490219 ILP78_RS12235 WP_000872881.1 2450877..2451446(-) (sigH) [Staphylococcus aureus strain MRSA - AMRF 6]
TTGAAATATGATTTGACAACGCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGAATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTTATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979