Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   IF715_RS02135 Genome accession   NZ_CP062418
Coordinates   397701..398387 (+) Length   228 a.a.
NCBI ID   WP_072353822.1    Uniprot ID   -
Organism   Staphylococcus aureus strain NAS_AN_136     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 392701..403387
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IF715_RS02100 (IF715_02085) yqeH 393228..394328 (+) 1101 WP_001280136.1 ribosome biogenesis GTPase YqeH -
  IF715_RS02105 (IF715_02090) aroE 394342..395148 (+) 807 WP_000666748.1 shikimate dehydrogenase -
  IF715_RS02110 (IF715_02095) yhbY 395152..395442 (+) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  IF715_RS02115 (IF715_02100) nadD 395445..396014 (+) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  IF715_RS02120 (IF715_02105) yqeK 396004..396588 (+) 585 WP_001019320.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  IF715_RS02125 (IF715_02110) rsfS 396589..396942 (+) 354 WP_001088020.1 ribosome silencing factor -
  IF715_RS02130 (IF715_02115) - 396945..397661 (+) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  IF715_RS02135 (IF715_02120) comEA 397701..398387 (+) 687 WP_072353822.1 ComEA family DNA-binding protein Machinery gene
  IF715_RS02140 (IF715_02125) - 398479..398940 (+) 462 WP_000439693.1 ComE operon protein 2 -
  IF715_RS02145 (IF715_02130) comEC 398945..401146 (+) 2202 WP_001815444.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  IF715_RS02150 (IF715_02135) holA 401203..402177 (+) 975 WP_001282562.1 DNA polymerase III subunit delta -
  IF715_RS02155 (IF715_02140) rpsT 402222..402473 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25773.50 Da        Isoelectric Point: 9.6753

>NTDB_id=489984 IF715_RS02135 WP_072353822.1 397701..398387(+) (comEA) [Staphylococcus aureus strain NAS_AN_136]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIGVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=489984 IF715_RS02135 WP_072353822.1 397701..398387(+) (comEA) [Staphylococcus aureus strain NAS_AN_136]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGGAGTAAACAGTGTGCATGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

99.561

100

0.996
  comEA Staphylococcus aureus N315

97.807

100

0.978