Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KFU87_RS12695 Genome accession   NZ_CP074019
Coordinates   2658521..2659177 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain PM22     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2653521..2664177
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KFU87_RS12665 (KFU87_12595) yecA 2654773..2655438 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  KFU87_RS12685 (KFU87_12615) pgsA 2656087..2656635 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KFU87_RS12690 (KFU87_12620) uvrC 2656692..2658524 (-) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  KFU87_RS12695 (KFU87_12625) letA 2658521..2659177 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KFU87_RS24630 - 2659319..2659435 (+) 117 WP_001302039.1 hypothetical protein -
  KFU87_RS12700 (KFU87_12630) yecU 2659473..2659649 (+) 177 WP_000590344.1 protein YecU -
  KFU87_RS12705 (KFU87_12635) yecF 2659636..2659860 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  KFU87_RS12710 (KFU87_12640) sdiA 2659928..2660650 (-) 723 WP_001154260.1 transcriptional regulator SdiA -
  KFU87_RS12715 (KFU87_12645) tcyN 2660880..2661632 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KFU87_RS12720 (KFU87_12650) tcyL 2661629..2662297 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  KFU87_RS12725 (KFU87_12655) dcyD 2662312..2663298 (-) 987 WP_001403670.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=489966 KFU87_RS12695 WP_000611328.1 2658521..2659177(-) (letA) [Escherichia coli strain PM22]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=489966 KFU87_RS12695 WP_000611328.1 2658521..2659177(-) (letA) [Escherichia coli strain PM22]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482