Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KFU74_RS10820 Genome accession   NZ_CP074007
Coordinates   2254752..2255408 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain PD4     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2249752..2260408
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KFU74_RS10790 (KFU74_10715) dcyD 2250632..2251618 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  KFU74_RS10795 (KFU74_10720) tcyL 2251633..2252301 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  KFU74_RS10800 (KFU74_10725) tcyN 2252298..2253050 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KFU74_RS10805 (KFU74_10730) sdiA 2253280..2254002 (+) 723 WP_001154268.1 transcriptional regulator SdiA -
  KFU74_RS10810 (KFU74_10735) yecF 2254069..2254293 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  KFU74_RS10815 (KFU74_10740) yecU 2254280..2254456 (-) 177 WP_001307856.1 protein YecU -
  KFU74_RS24370 - 2254539..2254610 (-) 72 Protein_2116 transcriptional regulator -
  KFU74_RS10820 (KFU74_10745) letA 2254752..2255408 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KFU74_RS10825 (KFU74_10750) uvrC 2255405..2257237 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  KFU74_RS10830 (KFU74_10755) pgsA 2257294..2257842 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KFU74_RS10850 (KFU74_10775) - 2258538..2259278 (-) 741 WP_059342797.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=489818 KFU74_RS10820 WP_000611335.1 2254752..2255408(+) (letA) [Escherichia coli strain PD4]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=489818 KFU74_RS10820 WP_000611335.1 2254752..2255408(+) (letA) [Escherichia coli strain PD4]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486