Detailed information NTG0489789

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: IF724_RS05535
• Genome accession: NZ_CP062413
• Coordinates: 1094443..1095429 (-)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain NAS_AN_176
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1089443..1100429

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF724_RS05510 (IF724_05505)	-	1089703..1090050 (-)	348	WP_001242103.1	hypothetical protein	-
IF724_RS05515 (IF724_05510)	-	1090236..1090829 (+)	594	WP_000224619.1	CYTH domain-containing protein	-
IF724_RS05520 (IF724_05515)	-	1090933..1091298 (+)	366	WP_000214070.1	truncated hemoglobin YjbI	-
IF724_RS05525 (IF724_05520)	yjbH	1091321..1092127 (+)	807	WP_000896697.1	protease adaptor protein YjbH	-
IF724_RS05530 (IF724_05525)	pepF	1092587..1094395 (-)	1809	WP_000082725.1	oligoendopeptidase F	-
IF724_RS05535 (IF724_05530)	coiA	1094443..1095429 (-)	987	WP_000959282.1	competence protein CoiA family protein	Machinery gene
IF724_RS05540 (IF724_05535)	mecA	1095550..1096269 (-)	720	WP_001217728.1	adaptor protein MecA	-
IF724_RS05545 (IF724_05540)	spxA	1096640..1097035 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
IF724_RS05550 (IF724_05545)	trpS	1097329..1098318 (+)	990	WP_000448934.1	tryptophan--tRNA ligase	-
IF724_RS05555 (IF724_05550)	opp4C	1098360..1099241 (-)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
IF724_RS05560 (IF724_05555)	opp4B	1099253..1100215 (-)	963	WP_000915997.1	oligopeptide ABC transporter permease	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=489789 IF724_RS05535 WP_000959282.1 1094443..1095429(-) (coiA) [Staphylococcus aureus strain NAS_AN_176]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=489789 IF724_RS05535 WP_000959282.1 1094443..1095429(-) (coiA) [Staphylococcus aureus strain NAS_AN_176]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976