Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   IF725_RS02200 Genome accession   NZ_CP062412
Coordinates   407601..408287 (+) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain NAS_AN_181     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 402601..413287
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IF725_RS02165 (IF725_02160) yqeH 403128..404228 (+) 1101 WP_001280138.1 ribosome biogenesis GTPase YqeH -
  IF725_RS02170 (IF725_02165) aroE 404242..405048 (+) 807 WP_000666757.1 shikimate dehydrogenase -
  IF725_RS02175 (IF725_02170) yhbY 405052..405342 (+) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  IF725_RS02180 (IF725_02175) nadD 405345..405914 (+) 570 WP_240100865.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  IF725_RS02185 (IF725_02180) yqeK 405904..406488 (+) 585 WP_001019323.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  IF725_RS02190 (IF725_02185) rsfS 406489..406842 (+) 354 WP_001088022.1 ribosome silencing factor -
  IF725_RS02195 (IF725_02190) - 406845..407561 (+) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  IF725_RS02200 (IF725_02195) comEA 407601..408287 (+) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  IF725_RS02205 (IF725_02200) - 408379..408840 (+) 462 WP_000439693.1 ComE operon protein 2 -
  IF725_RS02210 (IF725_02205) comEC 408845..411046 (+) 2202 WP_049308125.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  IF725_RS02215 (IF725_02210) holA 411103..412077 (+) 975 WP_001282562.1 DNA polymerase III subunit delta -
  IF725_RS02220 (IF725_02215) rpsT 412122..412373 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=489731 IF725_RS02200 WP_001792568.1 407601..408287(+) (comEA) [Staphylococcus aureus strain NAS_AN_181]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=489731 IF725_RS02200 WP_001792568.1 407601..408287(+) (comEA) [Staphylococcus aureus strain NAS_AN_181]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969