Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KFU69_RS09320 Genome accession   NZ_CP074005
Coordinates   1962426..1963082 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain PI12     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1957426..1968082
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KFU69_RS09290 (KFU69_09225) dcyD 1958306..1959292 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  KFU69_RS09295 (KFU69_09230) tcyL 1959307..1959975 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  KFU69_RS09300 (KFU69_09235) tcyN 1959972..1960724 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KFU69_RS09305 (KFU69_09240) sdiA 1960954..1961676 (+) 723 WP_001154265.1 transcriptional regulator SdiA -
  KFU69_RS09310 (KFU69_09245) yecF 1961743..1961967 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  KFU69_RS09315 (KFU69_09250) yecU 1961954..1962130 (-) 177 WP_001307856.1 protein YecU -
  KFU69_RS22765 - 1962213..1962284 (-) 72 Protein_1836 transcriptional regulator -
  KFU69_RS09320 (KFU69_09255) letA 1962426..1963082 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KFU69_RS09325 (KFU69_09260) uvrC 1963079..1964911 (+) 1833 WP_257161100.1 excinuclease ABC subunit UvrC Machinery gene
  KFU69_RS09330 (KFU69_09265) pgsA 1964968..1965516 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KFU69_RS09350 (KFU69_09285) yecA 1966166..1966831 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=489728 KFU69_RS09320 WP_000611328.1 1962426..1963082(+) (letA) [Escherichia coli strain PI12]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=489728 KFU69_RS09320 WP_000611328.1 1962426..1963082(+) (letA) [Escherichia coli strain PI12]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482