Detailed information NTG0489661

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: IF729_RS05500
• Genome accession: NZ_CP062410
• Coordinates: 1090965..1091951 (-)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain NAS_AN_205
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1085965..1096951

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF729_RS05475 (IF729_05460)	-	1086225..1086572 (-)	348	WP_001242103.1	hypothetical protein	-
IF729_RS05480 (IF729_05465)	-	1086758..1087351 (+)	594	WP_000224619.1	CYTH domain-containing protein	-
IF729_RS05485 (IF729_05470)	-	1087455..1087820 (+)	366	WP_000214070.1	truncated hemoglobin YjbI	-
IF729_RS05490 (IF729_05475)	yjbH	1087843..1088649 (+)	807	WP_000896697.1	protease adaptor protein YjbH	-
IF729_RS05495 (IF729_05480)	pepF	1089109..1090917 (-)	1809	WP_000082725.1	oligoendopeptidase F	-
IF729_RS05500 (IF729_05485)	coiA	1090965..1091951 (-)	987	WP_000959282.1	competence protein CoiA family protein	Machinery gene
IF729_RS05505 (IF729_05490)	mecA	1092072..1092791 (-)	720	WP_001217728.1	adaptor protein MecA	-
IF729_RS05510 (IF729_05495)	spxA	1093162..1093557 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
IF729_RS05515 (IF729_05500)	trpS	1093851..1094840 (+)	990	WP_000448934.1	tryptophan--tRNA ligase	-
IF729_RS05520 (IF729_05505)	opp4C	1094882..1095763 (-)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
IF729_RS05525 (IF729_05510)	opp4B	1095775..1096737 (-)	963	WP_000915997.1	oligopeptide ABC transporter permease	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=489661 IF729_RS05500 WP_000959282.1 1090965..1091951(-) (coiA) [Staphylococcus aureus strain NAS_AN_205]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=489661 IF729_RS05500 WP_000959282.1 1090965..1091951(-) (coiA) [Staphylococcus aureus strain NAS_AN_205]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976