Detailed information NTG0489618

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: IF734_RS05210
• Genome accession: NZ_CP062409
• Coordinates: 1052319..1053305 (-)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain NAS_AN_239
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1047319..1058305

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF734_RS05185 (IF734_05165)	-	1047579..1047926 (-)	348	WP_001242103.1	hypothetical protein	-
IF734_RS05190 (IF734_05170)	-	1048112..1048705 (+)	594	WP_000224619.1	CYTH domain-containing protein	-
IF734_RS05195 (IF734_05175)	-	1048809..1049174 (+)	366	WP_000214070.1	truncated hemoglobin YjbI	-
IF734_RS05200 (IF734_05180)	yjbH	1049197..1050003 (+)	807	WP_000896697.1	protease adaptor protein YjbH	-
IF734_RS05205 (IF734_05185)	pepF	1050463..1052271 (-)	1809	WP_000082725.1	oligoendopeptidase F	-
IF734_RS05210 (IF734_05190)	coiA	1052319..1053305 (-)	987	WP_000959282.1	competence protein CoiA family protein	Machinery gene
IF734_RS05215 (IF734_05195)	mecA	1053426..1054145 (-)	720	WP_001217728.1	adaptor protein MecA	-
IF734_RS05220 (IF734_05200)	spxA	1054516..1054911 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
IF734_RS05225 (IF734_05205)	trpS	1055205..1056194 (+)	990	WP_000448934.1	tryptophan--tRNA ligase	-
IF734_RS05230 (IF734_05210)	opp4C	1056236..1057117 (-)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
IF734_RS05235 (IF734_05215)	opp4B	1057129..1058091 (-)	963	WP_000915997.1	oligopeptide ABC transporter permease	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=489618 IF734_RS05210 WP_000959282.1 1052319..1053305(-) (coiA) [Staphylococcus aureus strain NAS_AN_239]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=489618 IF734_RS05210 WP_000959282.1 1052319..1053305(-) (coiA) [Staphylococcus aureus strain NAS_AN_239]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976