Detailed information NTG0489489

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: IF753_RS05195
• Genome accession: NZ_CP062406
• Coordinates: 1046846..1047832 (-)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain NAS_NP_198
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1041846..1052832

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF753_RS05170 (IF753_05155)	-	1042106..1042453 (-)	348	WP_001242103.1	hypothetical protein	-
IF753_RS05175 (IF753_05160)	-	1042639..1043232 (+)	594	WP_000224619.1	CYTH domain-containing protein	-
IF753_RS05180 (IF753_05165)	-	1043336..1043701 (+)	366	WP_000214070.1	truncated hemoglobin YjbI	-
IF753_RS05185 (IF753_05170)	yjbH	1043724..1044530 (+)	807	WP_000896697.1	protease adaptor protein YjbH	-
IF753_RS05190 (IF753_05175)	pepF	1044990..1046798 (-)	1809	WP_000082725.1	oligoendopeptidase F	-
IF753_RS05195 (IF753_05180)	coiA	1046846..1047832 (-)	987	WP_000959282.1	competence protein CoiA family protein	Machinery gene
IF753_RS05200 (IF753_05185)	mecA	1047953..1048672 (-)	720	WP_001217728.1	adaptor protein MecA	-
IF753_RS05205 (IF753_05190)	spxA	1049043..1049438 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
IF753_RS05210 (IF753_05195)	trpS	1049732..1050721 (+)	990	WP_000448934.1	tryptophan--tRNA ligase	-
IF753_RS05215 (IF753_05200)	opp4C	1050763..1051644 (-)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
IF753_RS05220 (IF753_05205)	opp4B	1051656..1052618 (-)	963	WP_000915997.1	oligopeptide ABC transporter permease	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=489489 IF753_RS05195 WP_000959282.1 1046846..1047832(-) (coiA) [Staphylococcus aureus strain NAS_NP_198]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=489489 IF753_RS05195 WP_000959282.1 1046846..1047832(-) (coiA) [Staphylococcus aureus strain NAS_NP_198]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976