Detailed information NTG0489461

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: IF754_RS12220
• Genome accession: NZ_CP062405
• Coordinates: 2403084..2403971 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143418.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain NAS_NP_209
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2398084..2408971

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF754_RS12190 (IF754_12140)	-	2398086..2398178 (+)	93	WP_031774855.1	hypothetical protein	-
IF754_RS12195 (IF754_12145)	-	2398286..2398783 (-)	498	WP_001065267.1	glutathione peroxidase	-
IF754_RS12200 (IF754_12150)	-	2398793..2399053 (-)	261	WP_001791293.1	hypothetical protein	-
IF754_RS12205 (IF754_12155)	-	2399435..2399548 (-)	114	WP_014937089.1	hypothetical protein	-
IF754_RS12210 (IF754_12160)	-	2400224..2402224 (-)	2001	WP_000776744.1	ABC transporter permease	-
IF754_RS12215 (IF754_12165)	-	2402221..2402976 (-)	756	WP_000923764.1	ABC transporter ATP-binding protein	-
IF754_RS12220 (IF754_12170)	braS	2403084..2403971 (-)	888	WP_000143418.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
IF754_RS12225 (IF754_12175)	braR	2403982..2404647 (-)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
IF754_RS12230 (IF754_12180)	-	2404673..2404873 (-)	201	WP_000604727.1	hypothetical protein	-
IF754_RS12235 (IF754_12185)	-	2405071..2406495 (+)	1425	WP_000953743.1	alkaline phosphatase	-
IF754_RS12240 (IF754_12190)	-	2406565..2406675 (+)	111	WP_001791296.1	hypothetical protein	-
IF754_RS12245 (IF754_12195)	-	2406778..2407233 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
IF754_RS12250 (IF754_12200)	-	2407478..2408239 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34105.41 Da
• Isoelectric Point: 5.8962

>NTDB_id=489461 IF754_RS12220 WP_000143418.1 2403084..2403971(-) (braS) [Staphylococcus aureus strain NAS_NP_209]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQFNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=489461 IF754_RS12220 WP_000143418.1 2403084..2403971(-) (braS) [Staphylococcus aureus strain NAS_NP_209]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAATTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATTCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99