Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KFU65_RS08975 Genome accession   NZ_CP073988
Coordinates   1848292..1848948 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain MB10     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1843292..1853948
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KFU65_RS08945 (KFU65_08870) dcyD 1844172..1845158 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  KFU65_RS08950 (KFU65_08875) tcyL 1845173..1845841 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  KFU65_RS08955 (KFU65_08880) tcyN 1845838..1846590 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KFU65_RS08960 (KFU65_08885) sdiA 1846820..1847542 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  KFU65_RS08965 (KFU65_08890) yecF 1847609..1847833 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  KFU65_RS08970 (KFU65_08895) yecU 1847820..1847996 (-) 177 WP_000590347.1 protein YecU -
  KFU65_RS23165 - 1848079..1848150 (-) 72 Protein_1757 transcriptional regulator -
  KFU65_RS08975 (KFU65_08900) letA 1848292..1848948 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KFU65_RS08980 (KFU65_08905) uvrC 1848945..1850777 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  KFU65_RS08985 (KFU65_08910) pgsA 1850834..1851382 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KFU65_RS09005 (KFU65_08930) - 1852076..1852815 (-) 740 Protein_1761 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=489409 KFU65_RS08975 WP_000611335.1 1848292..1848948(+) (letA) [Escherichia coli strain MB10]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=489409 KFU65_RS08975 WP_000611335.1 1848292..1848948(+) (letA) [Escherichia coli strain MB10]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486