Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   IF757_RS06600 Genome accession   NZ_CP062404
Coordinates   1340684..1341370 (-) Length   228 a.a.
NCBI ID   WP_001794049.1    Uniprot ID   A0A0E1X4U4
Organism   Staphylococcus aureus strain NAS_NP_229     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1336894..1350381 1340684..1341370 within 0


Gene organization within MGE regions


Location: 1336894..1350381
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IF757_RS06585 (IF757_06555) holA 1336894..1337868 (-) 975 WP_001282570.1 DNA polymerase III subunit delta -
  IF757_RS06590 (IF757_06560) comEC 1337925..1340126 (-) 2202 WP_000967506.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  IF757_RS06595 (IF757_06565) - 1340131..1340592 (-) 462 WP_000439692.1 ComE operon protein 2 -
  IF757_RS06600 (IF757_06570) comEA 1340684..1341370 (-) 687 WP_001794049.1 ComEA family DNA-binding protein Machinery gene
  IF757_RS06605 (IF757_06575) - 1341410..1342126 (-) 717 WP_000084835.1 class I SAM-dependent methyltransferase -
  IF757_RS06610 (IF757_06580) rsfS 1342129..1342482 (-) 354 WP_001088020.1 ribosome silencing factor -
  IF757_RS06615 (IF757_06585) yqeK 1342483..1343067 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  IF757_RS06620 (IF757_06590) nadD 1343057..1343626 (-) 570 WP_000822938.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  IF757_RS06625 (IF757_06595) yhbY 1343629..1343919 (-) 291 WP_000955232.1 ribosome assembly RNA-binding protein YhbY -
  IF757_RS06630 (IF757_06600) aroE 1343923..1344729 (-) 807 WP_000666750.1 shikimate dehydrogenase -
  IF757_RS06635 (IF757_06605) yqeH 1344743..1345843 (-) 1101 WP_001280134.1 ribosome biogenesis GTPase YqeH -
  IF757_RS06640 (IF757_06610) - 1345844..1346371 (-) 528 WP_000524902.1 YqeG family HAD IIIA-type phosphatase -
  IF757_RS06645 (IF757_06615) mtnN 1346391..1347077 (-) 687 WP_000579273.1 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase -
  IF757_RS06650 (IF757_06620) - 1347391..1347660 (+) 270 WP_000829750.1 hypothetical protein -
  IF757_RS06655 (IF757_06625) - 1347862..1348614 (-) 753 Protein_1305 exotoxin beta-grasp domain-containing protein -
  IF757_RS06660 (IF757_06630) - 1349162..1350381 (-) 1220 Protein_1306 Fic family protein -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25766.38 Da        Isoelectric Point: 9.3383

>NTDB_id=489406 IF757_RS06600 WP_001794049.1 1340684..1341370(-) (comEA) [Staphylococcus aureus strain NAS_NP_229]
MVLLYQFLLRYKDFLAQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTVLKQSTSENSSLSKLEDVQVKDGDNSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGANSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLNSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=489406 IF757_RS06600 WP_001794049.1 1340684..1341370(-) (comEA) [Staphylococcus aureus strain NAS_NP_229]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAGCTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
TTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTAGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGCAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAATTCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1X4U4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

95.595

99.561

0.952
  comEA Staphylococcus aureus N315

95.595

99.561

0.952