Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KFU92_RS09930 Genome accession   NZ_CP073984
Coordinates   2012440..2013096 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain MB15     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2007440..2018096
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KFU92_RS09900 (KFU92_09855) dcyD 2008320..2009306 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  KFU92_RS09905 (KFU92_09860) tcyL 2009321..2009989 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  KFU92_RS09910 (KFU92_09865) tcyN 2009986..2010738 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KFU92_RS09915 (KFU92_09870) sdiA 2010968..2011690 (+) 723 WP_032200101.1 transcriptional regulator SdiA -
  KFU92_RS09920 (KFU92_09875) yecF 2011757..2011981 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  KFU92_RS09925 (KFU92_09880) yecU 2011968..2012144 (-) 177 WP_001307856.1 protein YecU -
  KFU92_RS25200 - 2012227..2012298 (-) 72 Protein_1947 transcriptional regulator -
  KFU92_RS09930 (KFU92_09885) letA 2012440..2013096 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KFU92_RS09935 (KFU92_09890) uvrC 2013093..2014925 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  KFU92_RS09940 (KFU92_09895) pgsA 2014982..2015530 (+) 549 WP_032200177.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KFU92_RS09960 (KFU92_09915) yecA 2016180..2016845 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=489334 KFU92_RS09930 WP_000611335.1 2012440..2013096(+) (letA) [Escherichia coli strain MB15]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=489334 KFU92_RS09930 WP_000611335.1 2012440..2013096(+) (letA) [Escherichia coli strain MB15]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486