Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KFU84_RS16855 Genome accession   NZ_CP073981
Coordinates   3537295..3537951 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain MB19     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3532295..3542951
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KFU84_RS16825 (KFU84_16690) dcyD 3533175..3534161 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  KFU84_RS16830 (KFU84_16695) tcyL 3534176..3534844 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  KFU84_RS16835 (KFU84_16700) tcyN 3534841..3535593 (+) 753 WP_257182082.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KFU84_RS16840 (KFU84_16705) sdiA 3535823..3536545 (+) 723 WP_001154275.1 transcriptional regulator SdiA -
  KFU84_RS16845 (KFU84_16710) yecF 3536612..3536836 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  KFU84_RS16850 (KFU84_16715) yecU 3536823..3536999 (-) 177 WP_032160694.1 protein YecU -
  KFU84_RS16855 (KFU84_16720) letA 3537295..3537951 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KFU84_RS16860 (KFU84_16725) uvrC 3537948..3539780 (+) 1833 WP_257182083.1 excinuclease ABC subunit UvrC Machinery gene
  KFU84_RS16865 (KFU84_16730) pgsA 3539837..3540385 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KFU84_RS16885 (KFU84_16750) yecA 3541035..3541700 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=489285 KFU84_RS16855 WP_000611328.1 3537295..3537951(+) (letA) [Escherichia coli strain MB19]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=489285 KFU84_RS16855 WP_000611328.1 3537295..3537951(+) (letA) [Escherichia coli strain MB19]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482