Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   IF777_RS02585 Genome accession   NZ_CP062399
Coordinates   549773..550342 (+) Length   189 a.a.
NCBI ID   WP_045174125.1    Uniprot ID   -
Organism   Staphylococcus aureus strain NAS_OP_143     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 544773..555342
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IF777_RS02560 (IF777_02550) cysE 545986..546633 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  IF777_RS02565 (IF777_02555) cysS 546617..548017 (+) 1401 WP_000631974.1 cysteine--tRNA ligase -
  IF777_RS02570 (IF777_02560) - 548010..548414 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  IF777_RS02575 (IF777_02565) rlmB 548422..549168 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  IF777_RS02580 (IF777_02570) - 549168..549692 (+) 525 WP_000664738.1 NYN domain-containing protein -
  IF777_RS02585 (IF777_02575) sigH 549773..550342 (+) 570 WP_045174125.1 RNA polymerase sigma factor Regulator
  IF777_RS02590 (IF777_02580) rpmG 550457..550600 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  IF777_RS02595 (IF777_02585) secE 550656..550838 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  IF777_RS02600 (IF777_02590) nusG 550851..551399 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  IF777_RS02605 (IF777_02595) rplK 551580..552002 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  IF777_RS02610 (IF777_02600) rplA 552210..552902 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  IF777_RS02615 (IF777_02605) rplJ 553174..553674 (+) 501 WP_001273087.1 50S ribosomal protein L10 -
  IF777_RS02620 (IF777_02610) rplL 553717..554085 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  IF777_RS02625 (IF777_02615) - 554260..554868 (+) 609 WP_240053287.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.91 Da        Isoelectric Point: 9.5047

>NTDB_id=489181 IF777_RS02585 WP_045174125.1 549773..550342(+) (sigH) [Staphylococcus aureus strain NAS_OP_143]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNQLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=489181 IF777_RS02585 WP_045174125.1 549773..550342(+) (sigH) [Staphylococcus aureus strain NAS_OP_143]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATCAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979