Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   SGGB_RS06470 Genome accession   NC_017576
Coordinates   1295305..1296534 (-) Length   409 a.a.
NCBI ID   WP_012962047.1    Uniprot ID   -
Organism   Streptococcus gallolyticus subsp. gallolyticus ATCC 43143     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1290305..1301534
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGGB_RS06445 (SGGB_1244) - 1290602..1291249 (+) 648 WP_012962042.1 endonuclease III domain-containing protein -
  SGGB_RS06450 (SGGB_1245) - 1291358..1292026 (+) 669 WP_039694591.1 YoaK family protein -
  SGGB_RS06455 (SGGB_1246) mmuM 1292066..1293013 (-) 948 WP_012962044.1 homocysteine S-methyltransferase -
  SGGB_RS06460 (SGGB_1247) - 1293026..1294402 (-) 1377 WP_012962045.1 amino acid permease -
  SGGB_RS06465 (SGGB_1248) yihA 1294701..1295294 (-) 594 WP_012962046.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  SGGB_RS06470 (SGGB_1249) clpX 1295305..1296534 (-) 1230 WP_012962047.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  SGGB_RS12055 (SGGB_1250) - 1296567..1296737 (-) 171 WP_003065196.1 hypothetical protein -
  SGGB_RS06480 (SGGB_1251) - 1296754..1297248 (-) 495 WP_012962048.1 dihydrofolate reductase -
  SGGB_RS06485 (SGGB_1252) - 1297336..1298175 (-) 840 WP_009854362.1 thymidylate synthase -
  SGGB_RS06490 (SGGB_1253) - 1298497..1299675 (+) 1179 WP_012962049.1 hydroxymethylglutaryl-CoA synthase -
  SGGB_RS06495 (SGGB_1254) - 1299650..1300933 (+) 1284 WP_014620161.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45154.77 Da        Isoelectric Point: 4.5644

>NTDB_id=48918 SGGB_RS06470 WP_012962047.1 1295305..1296534(-) (clpX) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
MVGNRTNDVKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLATLDEYVVGQDR
AKRALAVAVYNHYKRVSFAESRNEEDVDLQKSNILMIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEDIVKQRLGEKVIGFGQNNRKIDENASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLTADDLVRI
LTEPRNALVKQYQTLLSYDGVELEFDKDALQAIANKAIERKTGARGLRSIIEETMMDIMFEIPSQEEVTKVRITKAAVEG
KDKPILEIA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=48918 SGGB_RS06470 WP_012962047.1 1295305..1296534(-) (clpX) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
ATGGTTGGAAATCGAACAAATGATGTAAAAGTTTATTGCTCATTCTGTGGAAAAAGCCAAGATGAAGTAAAAAAAATCAT
TGCAGGAAACAATGTTTTTATCTGTAATGAGTGTGTGGCTTTGTCACAAGAAATTATCAAAGAAGAACTTGCTGAAGAAG
TTCTTGCAGATTTAGCGGAAGTTCCAAAACCTAAAGAGTTGTTAGCAACTCTTGACGAATATGTCGTTGGTCAAGATCGT
GCCAAACGCGCGCTTGCCGTAGCTGTTTATAACCATTACAAACGTGTTTCTTTTGCGGAAAGTCGCAACGAAGAAGATGT
TGATTTGCAAAAATCAAACATTTTGATGATTGGTCCTACAGGCTCAGGAAAAACATTCCTAGCTCAAACTTTGGCTAAAA
CATTGAATGTACCGTTTGCGATTGCTGATGCGACATCATTGACAGAAGCAGGATACGTTGGTGAAGATGTTGAAAATATC
CTCTTGAAATTAATTCAAGCAGCTGATTTTAATATCGAACGCGCCGAACGCGGTATTATTTACGTGGATGAAATTGATAA
AATCGCTAAAAAAGGTGAAAATGTCTCAATTACACGTGATGTTTCAGGTGAAGGTGTTCAACAAGCACTTCTTAAAATCA
TTGAAGGAACAGTTGCTAGCGTACCACCTCAAGGTGGACGTAAGCACCCTAACCAAGAAATGATTCAAATTGACACTAAA
AATATCCTATTCATTGTCGGCGGTGCTTTTGATGGTATCGAAGATATTGTCAAACAACGTTTAGGTGAAAAGGTTATCGG
TTTTGGTCAAAATAACCGTAAAATTGATGAAAATGCTTCTTATATGCAAGAAATCATTTCAGAAGATATTCAAAAATTTG
GCTTGATTCCAGAGTTTATCGGACGTTTGCCAGTTGTTGCGGCACTTGAACAGTTGACGGCTGATGATTTGGTTCGTATC
TTGACAGAACCACGTAATGCCTTGGTTAAACAATATCAAACGCTATTATCATACGACGGTGTTGAACTAGAATTTGATAA
AGATGCTTTGCAAGCTATTGCTAACAAAGCCATTGAACGCAAGACAGGAGCTCGTGGTTTACGCTCAATTATTGAAGAAA
CTATGATGGATATCATGTTTGAAATTCCTAGCCAAGAAGAAGTGACTAAGGTTCGTATCACTAAAGCGGCTGTTGAAGGC
AAAGACAAACCAATTTTGGAAATTGCGTAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-391)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.976

100

0.9
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.603

98.044

0.575

Multiple sequence alignment