Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KFU64_RS08890 Genome accession   NZ_CP073976
Coordinates   1874480..1875136 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain MB20     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1869480..1880136
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KFU64_RS08860 (KFU64_08780) dcyD 1870359..1871345 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  KFU64_RS08865 (KFU64_08785) tcyL 1871360..1872028 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  KFU64_RS08870 (KFU64_08790) tcyN 1872025..1872777 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KFU64_RS08875 (KFU64_08795) sdiA 1873007..1873729 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  KFU64_RS08880 (KFU64_08800) yecF 1873797..1874021 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  KFU64_RS08885 (KFU64_08805) yecU 1874008..1874184 (-) 177 WP_257182552.1 protein YecU -
  KFU64_RS24700 - 1874222..1874338 (-) 117 WP_001302039.1 hypothetical protein -
  KFU64_RS08890 (KFU64_08810) letA 1874480..1875136 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KFU64_RS08895 (KFU64_08815) uvrC 1875133..1876965 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  KFU64_RS08900 (KFU64_08820) pgsA 1877022..1877570 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KFU64_RS08920 (KFU64_08840) - 1878150..1879160 (-) 1011 WP_121851498.1 tyrosine-type recombinase/integrase -
  KFU64_RS08925 (KFU64_08845) - 1879160..1879387 (-) 228 WP_257182553.1 DUF4224 domain-containing protein -
  KFU64_RS08930 - 1879702..1879860 (-) 159 Protein_1741 chromosome partitioning protein ParB -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=489175 KFU64_RS08890 WP_000611328.1 1874480..1875136(+) (letA) [Escherichia coli strain MB20]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=489175 KFU64_RS08890 WP_000611328.1 1874480..1875136(+) (letA) [Escherichia coli strain MB20]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482