Detailed information NTG0489129

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: IF694_RS10170
• Genome accession: NZ_CP062395
• Coordinates: 2106594..2107481 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain NAS_AN_005
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2101594..2112481

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF694_RS10140 (IF694_10020)	-	2102326..2103087 (+)	762	WP_000323448.1	alpha/beta hydrolase family protein	-
IF694_RS10145 (IF694_10025)	-	2103332..2103787 (+)	456	WP_047213013.1	MarR family winged helix-turn-helix transcriptional regulator	-
IF694_RS14045	-	2103909..2104010 (+)	102	WP_000731972.1	SE2200 family small protein	-
IF694_RS10155 (IF694_10035)	-	2104070..2105494 (-)	1425	WP_047213011.1	alkaline phosphatase	-
IF694_RS10160 (IF694_10040)	-	2105692..2105892 (+)	201	WP_000604725.1	hypothetical protein	-
IF694_RS10165 (IF694_10045)	braR	2105918..2106583 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
IF694_RS10170 (IF694_10050)	braS	2106594..2107481 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
IF694_RS10175 (IF694_10055)	-	2107589..2108344 (+)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
IF694_RS10180 (IF694_10060)	-	2108341..2110341 (+)	2001	WP_042907889.1	ABC transporter permease	-
IF694_RS10185 (IF694_10065)	-	2111006..2111119 (+)	114	WP_072357681.1	hypothetical protein	-
IF694_RS10190 (IF694_10070)	-	2111501..2111761 (+)	261	WP_240022112.1	hypothetical protein	-
IF694_RS10195 (IF694_10075)	-	2111771..2112268 (+)	498	WP_001065267.1	glutathione peroxidase	-
IF694_RS10200 (IF694_10080)	-	2112376..2112468 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=489129 IF694_RS10170 WP_000143420.1 2106594..2107481(+) (braS) [Staphylococcus aureus strain NAS_AN_005]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=489129 IF694_RS10170 WP_000143420.1 2106594..2107481(+) (braS) [Staphylococcus aureus strain NAS_AN_005]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993