Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   KFU73_RS16525 Genome accession   NZ_CP073974
Coordinates   3409503..3410627 (+) Length   374 a.a.
NCBI ID   WP_053887501.1    Uniprot ID   -
Organism   Escherichia coli strain MB22     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 3404503..3415627
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KFU73_RS16500 (KFU73_16335) mscL 3404629..3405039 (-) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -
  KFU73_RS16505 (KFU73_16340) trkA 3405169..3406545 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  KFU73_RS16510 (KFU73_16345) rsmB 3406567..3407856 (-) 1290 WP_000744778.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  KFU73_RS16515 (KFU73_16350) fmt 3407902..3408849 (-) 948 WP_112919307.1 methionyl-tRNA formyltransferase -
  KFU73_RS16520 (KFU73_16355) def 3408864..3409373 (-) 510 WP_000114984.1 peptide deformylase -
  KFU73_RS16525 (KFU73_16360) dprA 3409503..3410627 (+) 1125 WP_053887501.1 DNA-protecting protein DprA Machinery gene
  KFU73_RS16530 (KFU73_16365) smg 3410599..3411072 (+) 474 WP_112919308.1 DUF494 family protein Smg -
  KFU73_RS16535 (KFU73_16370) yrdD 3411101..3411643 (+) 543 WP_001129722.1 type I DNA topoisomerase -
  KFU73_RS16540 (KFU73_16375) tsaC 3411648..3412220 (+) 573 WP_001301412.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  KFU73_RS16545 (KFU73_16380) aroE 3412225..3413043 (+) 819 WP_033802958.1 shikimate dehydrogenase -
  KFU73_RS16550 (KFU73_16385) yrdB 3413040..3413297 (+) 258 WP_001070563.1 DUF1488 domain-containing protein -
  KFU73_RS16555 (KFU73_16390) yrdA 3413273..3413827 (-) 555 WP_001286216.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 41001.00 Da        Isoelectric Point: 6.3114

>NTDB_id=489116 KFU73_RS16525 WP_053887501.1 3409503..3410627(+) (dprA) [Escherichia coli strain MB22]
MVDTEIWLRLMSISSLYGDDMVRIAHWVAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
CVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=489116 KFU73_RS16525 WP_053887501.1 3409503..3410627(+) (dprA) [Escherichia coli strain MB22]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATCGCTCACTG
GGTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCACGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATTCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT
TGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT
TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (WHD_DprA)

(312-357)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

47.967

98.663

0.473
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

49.032

82.888

0.406
  dprA Vibrio cholerae strain A1552

49.032

82.888

0.406
  dprA Haemophilus influenzae Rd KW20

44.807

90.107

0.404
  dprA Glaesserella parasuis strain SC1401

44.51

90.107

0.401
  dprA Legionella pneumophila strain ERS1305867

43.939

88.235

0.388