Detailed information NTG0048911

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: SGGB_RS03485
• Genome accession: NC_017576
• Coordinates: 658894..661125 (+)
• Length: 743 a.a.
• NCBI ID: WP_014619988.1
• Uniprot ID: -
• Organism: Streptococcus gallolyticus subsp. gallolyticus ATCC 43143
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 653894..666125

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGGB_RS03460 (SGGB_0632)	-	654667..656247 (+)	1581	WP_013642855.1	DEAD/DEAH box helicase	-
SGGB_RS03465 (SGGB_0633)	-	656291..656554 (-)	264	WP_305727931.1	GIY-YIG nuclease family protein	-
SGGB_RS03470 (SGGB_0634)	-	656538..657287 (-)	750	WP_013642857.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
SGGB_RS03475 (SGGB_0635)	-	657395..658141 (+)	747	WP_009853766.1	lysophospholipid acyltransferase family protein	-
SGGB_RS03480 (SGGB_0636)	comEA	658236..658901 (+)	666	WP_013642858.1	helix-hairpin-helix domain-containing protein	Machinery gene
SGGB_RS03485 (SGGB_0637)	comEC/celB	658894..661125 (+)	2232	WP_014619988.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SGGB_RS03490 (SGGB_0638)	-	661187..661375 (+)	189	WP_013642860.1	type II toxin-antitoxin system HicA family toxin	-
SGGB_RS03495 (SGGB_0639)	-	661415..661792 (+)	378	WP_013642861.1	type II toxin-antitoxin system HicB family antitoxin	-
SGGB_RS03500 (SGGB_0640)	-	661876..662454 (+)	579	WP_013642862.1	HD domain-containing protein	-
SGGB_RS03505 (SGGB_0641)	-	662457..662993 (+)	537	WP_231844605.1	hypothetical protein	-
SGGB_RS03510 (SGGB_0643)	holA	663239..664276 (+)	1038	WP_009853769.1	DNA polymerase III subunit delta	-
SGGB_RS03515 (SGGB_0644)	sodA	664365..664973 (+)	609	WP_014619989.1	superoxide dismutase SodA	-
SGGB_RS03520 (SGGB_0645)	-	665125..665850 (+)	726	WP_012961667.1	YebC/PmpR family DNA-binding transcriptional regulator	-

Sequence

Protein

• Length: 743 a.a.
• Molecular weight: 83882.27 Da
• Isoelectric Point: 8.6237

>NTDB_id=48911 SGGB_RS03485 WP_014619988.1 658894..661125(+) (comEC/celB) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
MIKYFPIKPIQLTFLLILLYYFCFSKMIGCLMFLLLALVFLWQQYGWKTWCQVCLCLSCFAVFFLTKSNQTEQAYQAAPA
HLTKIQMIPDTISVNGDLLSFRGKEAGRTYQIFYTLKSEKEQHFFKTLNQTVVLSGDMDLEEATPQRNFGGFDYRTYLKH
EGIYRVVNLSAINNVELVYKMTLWEKLHDVRRKAIVSIQRHFPAPMQHYMTGLLFGYLDKSFDEMSDVYTSLGIIHLFAL
SGMQVGFFVGAFRFFFLRLGLRRDYVDILQIPFSLVYAGLTGFSVSVIRSLIQSAFANLGIKKLDNLALTLFVLFIVMPN
FLLTTGGILSFTYAFILSFINFDDISRYQKIIAESLTISLASLPLLIHFFAVFQPLSVLLTAIFSVAFDTIMLPMLSLIF
ILSPLVKLTCFNGCFVFLETVIKNTKAILGGPIVFGKPSLGILVLLFLTLGVLYDCWRRKKMAIFLVSLVGLLFFQIKHP
LENEVTVVDIGQGDSIFVRDVKGHTLLIDVGGKVSFSEKNAWQERLTDSNAERTLIPYLNSRGVGKIDQLVLTHTDTDHM
GDMLEVAKQVKIGEILVSQGSLTKPDFVAKLQAMKTKVRVVTAGDVLPIMGSHLQVLYPSQTGDGGNNDSVVLYGNLLGK
NFLFTGDLEEEGEQELIATYPNLPVDVLKAGHHGSKGSSSSEFLAHISPQIALISAGQNNRYKHPHQETLERFRAQNMTI
YRTDEQGAIRFRGLNHWKIETVR

Nucleotide

• Length: 2232 bp

>NTDB_id=48911 SGGB_RS03485 WP_014619988.1 658894..661125(+) (comEC/celB) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
TTGATTAAATATTTTCCCATTAAGCCAATTCAATTGACTTTTTTGCTCATTTTGCTCTATTATTTTTGCTTTTCAAAAAT
GATTGGGTGTTTGATGTTTCTCTTGCTAGCCTTGGTGTTTTTATGGCAACAGTATGGTTGGAAGACTTGGTGTCAAGTTT
GCTTGTGTTTAAGCTGTTTTGCGGTATTTTTTCTGACTAAGTCTAATCAGACAGAGCAGGCTTATCAAGCAGCACCAGCT
CATTTAACAAAAATCCAGATGATTCCTGACACGATTTCGGTCAATGGGGATTTGCTGTCCTTTCGAGGTAAGGAAGCTGG
GCGGACTTATCAGATTTTTTATACCTTGAAATCGGAGAAAGAACAGCATTTTTTTAAGACATTAAATCAAACGGTTGTTT
TATCTGGTGATATGGACTTGGAAGAAGCAACGCCCCAGCGGAATTTTGGTGGTTTTGATTATCGTACTTACCTTAAACAT
GAAGGCATTTATCGTGTGGTAAATTTGTCGGCGATTAACAATGTTGAACTTGTTTATAAGATGACTTTGTGGGAGAAGCT
ACATGATGTTCGACGAAAGGCTATTGTTAGTATTCAGCGGCATTTTCCTGCTCCTATGCAACATTATATGACTGGGCTTT
TGTTTGGCTATCTGGATAAATCGTTTGATGAGATGAGTGATGTTTACACGAGTTTAGGAATTATTCACCTCTTTGCTCTT
TCAGGCATGCAGGTCGGCTTTTTTGTGGGGGCATTCCGCTTTTTCTTTCTACGTCTTGGGTTACGCCGAGATTATGTGGA
CATACTACAAATTCCATTTTCACTCGTCTATGCGGGGCTGACTGGCTTTTCTGTTTCGGTGATTCGGAGTTTAATTCAGT
CTGCTTTTGCAAATCTTGGTATTAAAAAATTAGATAACTTAGCTTTAACTTTGTTTGTTCTTTTCATAGTTATGCCAAAT
TTTCTGCTGACGACGGGAGGCATTCTTTCGTTTACTTACGCTTTTATTCTCAGTTTTATTAACTTTGATGACATTAGTCG
CTATCAGAAAATCATTGCGGAAAGTTTGACGATTTCATTAGCCAGTTTGCCCTTGTTAATTCATTTTTTTGCTGTGTTTC
AACCGTTATCTGTCTTATTGACAGCAATTTTTTCTGTGGCATTTGACACTATTATGTTGCCAATGCTATCACTCATTTTT
ATTTTATCGCCCTTGGTTAAACTGACTTGTTTTAATGGTTGTTTTGTTTTCTTGGAAACTGTTATCAAGAACACTAAGGC
AATTTTGGGCGGTCCGATTGTTTTTGGGAAACCAAGTCTTGGTATCTTGGTGCTGCTATTTTTAACATTAGGCGTGCTTT
ATGATTGCTGGCGACGAAAGAAAATGGCAATTTTTCTTGTCAGCTTAGTAGGTCTGCTATTTTTTCAAATCAAGCATCCG
CTAGAAAACGAGGTGACGGTGGTTGATATTGGGCAGGGAGATAGTATTTTTGTGCGTGATGTTAAGGGGCATACGCTGCT
AATTGATGTGGGCGGAAAGGTGAGTTTTAGTGAGAAGAACGCGTGGCAGGAGCGGCTGACGGATAGCAATGCGGAGCGAA
CGTTGATTCCTTATCTCAACAGTCGCGGCGTTGGAAAAATTGACCAGTTAGTTCTGACGCACACGGATACTGACCACATG
GGAGATATGCTGGAAGTGGCAAAGCAGGTGAAAATTGGTGAAATTCTGGTTAGTCAGGGAAGTTTGACAAAGCCAGATTT
TGTGGCGAAATTACAAGCCATGAAAACCAAGGTGCGCGTGGTAACAGCTGGTGATGTTTTGCCGATTATGGGAAGTCACC
TGCAAGTGCTTTATCCGAGCCAGACTGGTGATGGTGGTAACAATGACTCGGTGGTGCTTTATGGGAATCTTTTGGGTAAG
AATTTCTTGTTTACAGGAGATTTGGAAGAAGAAGGCGAGCAAGAGTTAATAGCAACTTATCCCAATCTGCCGGTTGATGT
CTTAAAAGCAGGACATCATGGCTCAAAAGGGTCATCAAGCTCAGAATTTCTCGCTCACATTTCACCGCAAATTGCTTTGA
TTTCCGCAGGGCAAAATAACCGCTACAAACATCCTCATCAAGAAACGCTTGAACGCTTCCGAGCACAAAACATGACCATT
TACCGTACAGACGAACAAGGCGCTATCCGCTTTAGAGGATTAAACCACTGGAAAATCGAAACAGTGAGGTAG

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (27-174)

• Competence protein (Competence) (213-459)

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-697)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	52.695	99.865	0.526
comEC/celB	Streptococcus mitis SK321	52.291	99.865	0.522
comEC/celB	Streptococcus pneumoniae TIGR4	51.144	100	0.511
comEC/celB	Streptococcus pneumoniae Rx1	50.606	100	0.506
comEC/celB	Streptococcus pneumoniae D39	50.606	100	0.506
comEC/celB	Streptococcus pneumoniae R6	50.606	100	0.506
comEC	Lactococcus lactis subsp. cremoris KW2	47.914	100	0.479