Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KFU82_RS09450 Genome accession   NZ_CP073968
Coordinates   1941993..1942649 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain MB30     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1936993..1947649
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KFU82_RS09420 (KFU82_09360) dcyD 1937872..1938858 (+) 987 WP_001695857.1 D-cysteine desulfhydrase -
  KFU82_RS09425 (KFU82_09365) tcyL 1938873..1939541 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  KFU82_RS09430 (KFU82_09370) tcyN 1939538..1940290 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KFU82_RS09435 (KFU82_09375) sdiA 1940520..1941242 (+) 723 WP_104773718.1 transcriptional regulator SdiA -
  KFU82_RS09440 (KFU82_09380) yecF 1941310..1941534 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  KFU82_RS09445 (KFU82_09385) yecU 1941521..1941697 (-) 177 WP_000590344.1 protein YecU -
  KFU82_RS26120 - 1941735..1941851 (-) 117 WP_001302039.1 hypothetical protein -
  KFU82_RS09450 (KFU82_09390) letA 1941993..1942649 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KFU82_RS09455 (KFU82_09395) uvrC 1942646..1944478 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  KFU82_RS09460 (KFU82_09400) pgsA 1944535..1945083 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KFU82_RS09480 (KFU82_09420) - 1945779..1946519 (-) 741 WP_063078870.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=489014 KFU82_RS09450 WP_000611335.1 1941993..1942649(+) (letA) [Escherichia coli strain MB30]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=489014 KFU82_RS09450 WP_000611335.1 1941993..1942649(+) (letA) [Escherichia coli strain MB30]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486