Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   IF702_RS02050 Genome accession   NZ_CP062384
Coordinates   380848..381534 (+) Length   228 a.a.
NCBI ID   WP_072468915.1    Uniprot ID   A0A5F0HFN7
Organism   Staphylococcus aureus strain NAS_AN_050     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 375848..386534
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IF702_RS02015 (IF702_02010) yqeH 376375..377475 (+) 1101 WP_001280146.1 ribosome biogenesis GTPase YqeH -
  IF702_RS02020 (IF702_02015) aroE 377489..378295 (+) 807 WP_042744294.1 shikimate dehydrogenase -
  IF702_RS02025 (IF702_02020) yhbY 378299..378589 (+) 291 WP_000955234.1 ribosome assembly RNA-binding protein YhbY -
  IF702_RS02030 (IF702_02025) nadD 378592..379161 (+) 570 WP_000725165.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  IF702_RS02035 (IF702_02030) yqeK 379151..379735 (+) 585 WP_001017837.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  IF702_RS02040 (IF702_02035) rsfS 379736..380089 (+) 354 WP_001088020.1 ribosome silencing factor -
  IF702_RS02045 (IF702_02040) - 380092..380808 (+) 717 WP_000084840.1 class I SAM-dependent methyltransferase -
  IF702_RS02050 (IF702_02045) comEA 380848..381534 (+) 687 WP_072468915.1 ComEA family DNA-binding protein Machinery gene
  IF702_RS02055 (IF702_02050) - 381626..382087 (+) 462 WP_000439693.1 ComE operon protein 2 -
  IF702_RS02060 (IF702_02055) comEC 382092..384293 (+) 2202 WP_240024017.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  IF702_RS02065 (IF702_02060) holA 384350..385324 (+) 975 WP_001282573.1 DNA polymerase III subunit delta -
  IF702_RS02070 (IF702_02065) rpsT 385369..385620 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25812.41 Da        Isoelectric Point: 9.3305

>NTDB_id=488895 IF702_RS02050 WP_072468915.1 380848..381534(+) (comEA) [Staphylococcus aureus strain NAS_AN_050]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTALKQSTSENSSLSKLEDVQAKDGDNSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGENSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=488895 IF702_RS02050 WP_072468915.1 380848..381534(+) (comEA) [Staphylococcus aureus strain NAS_AN_050]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGCCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACACCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGAAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5F0HFN7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

96.476

99.561

0.961
  comEA Staphylococcus aureus N315

96.476

99.561

0.961