NTDB

Overview

Name	coiA	Type	Machinery gene
Locus tag	IF704_RS05900	Genome accession	NZ_CP062380
Coordinates	1155074..1156060 (-)	Length	328 a.a.
NCBI ID	WP_000959278.1	Uniprot ID	A0A6B5F529
Organism	Staphylococcus aureus strain NAS_AN_076
Function	require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1150074..1161060

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF704_RS05875 (IF704_05805)	-	1150333..1150680 (-)	348	WP_001242107.1	hypothetical protein	-
IF704_RS05880 (IF704_05810)	-	1150866..1151459 (+)	594	WP_000224616.1	CYTH domain-containing protein	-
IF704_RS05885 (IF704_05815)	-	1151563..1151928 (+)	366	WP_000214067.1	truncated hemoglobin YjbI	-
IF704_RS05890 (IF704_05820)	yjbH	1151951..1152757 (+)	807	WP_000896694.1	protease adaptor protein YjbH	-
IF704_RS05895 (IF704_05825)	pepF	1153218..1155026 (-)	1809	WP_000082725.1	oligoendopeptidase F	-
IF704_RS05900 (IF704_05830)	coiA	1155074..1156060 (-)	987	WP_000959278.1	competence protein CoiA family protein	Machinery gene
IF704_RS05905 (IF704_05835)	mecA	1156181..1156900 (-)	720	WP_001217727.1	adaptor protein MecA	-
IF704_RS05910 (IF704_05840)	spxA	1157281..1157676 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
IF704_RS05915 (IF704_05845)	trpS	1157971..1158960 (+)	990	WP_000448929.1	tryptophan--tRNA ligase	-
IF704_RS05920 (IF704_05850)	opp4C	1159002..1159883 (-)	882	WP_001180269.1	oligopeptide ABC transporter permease	-
IF704_RS05925 (IF704_05855)	opp4B	1159895..1160857 (-)	963	WP_000593417.1	oligopeptide ABC transporter permease	-

Sequence

Protein

Download Length: 328 a.a. Molecular weight: 38679.31 Da Isoelectric Point: 9.5882

                                >NTDB_id=488830 IF704_RS05900 WP_000959278.1 1155074..1156060(-) (coiA) [Staphylococcus aureus strain NAS_AN_076]

MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNESIKHYKSKLILAQMIQQQGCKV

EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFQSMFINPITRKL

HTFNLEKKQIMMFQQIQYIGGHKYVAEKGNAKISELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ

LTVQEVVHNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLLSDNLNYFKLKKFIVALDSKTAIIEKLINNYLNICSDR

GNDVQILF

Nucleotide

Download Length: 987 bp

                                >NTDB_id=488830 IF704_RS05900 WP_000959278.1 1155074..1156060(-) (coiA) [Staphylococcus aureus strain NAS_AN_076]

ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGCGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCGGT

GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT

GTTTTAATAATGAATCGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA

GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA

TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA

ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCAAAGTATGTTTATTAATCCAATCACTCGAAAACTT

CATACGTTTAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATATAGGCGGGCACAAATATGTCGCTGA

AAAAGGGAATGCCAAAATTAGTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTTG

CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAGTTACAG

TTAACTGTTCAAGAAGTAGTGCACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG

GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTACTAAGTGACAATCTTAATTATTTTAAACTGAAAA

AGTTTATTGTTGCTCTAGATAGCAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA

GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

Competence protein CoiA-like family (CoiA_nuc)

(6-288)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A6B5F529

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
coiA	Staphylococcus aureus N315	96.646	100	0.966
coiA	Staphylococcus aureus MW2	96.646	100	0.966

Detailed information NTG0488830