Detailed information NTG0488719

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: IF710_RS12760
• Genome accession: NZ_CP062372
• Coordinates: 2593946..2594833 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain NAS_AN_109
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2588946..2599833

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF710_RS12730 (IF710_12665)	-	2588964..2589056 (+)	93	WP_010956583.1	hypothetical protein	-
IF710_RS12735 (IF710_12670)	-	2589164..2589661 (-)	498	WP_001065269.1	glutathione peroxidase	-
IF710_RS12740 (IF710_12675)	-	2589671..2589931 (-)	261	WP_001789910.1	hypothetical protein	-
IF710_RS12745 (IF710_12680)	-	2590313..2590426 (-)	114	Protein_2472	hypothetical protein	-
IF710_RS12750 (IF710_12685)	-	2591085..2593085 (-)	2001	WP_000776739.1	ABC transporter permease	-
IF710_RS12755 (IF710_12690)	-	2593082..2593837 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
IF710_RS12760 (IF710_12695)	braS	2593946..2594833 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
IF710_RS12765 (IF710_12700)	braR	2594844..2595509 (-)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
IF710_RS12770 (IF710_12705)	-	2595535..2595735 (-)	201	WP_000604727.1	hypothetical protein	-
IF710_RS12775 (IF710_12710)	-	2595933..2597357 (+)	1425	WP_000953762.1	alkaline phosphatase	-
IF710_RS12780 (IF710_12715)	-	2597427..2597537 (+)	111	WP_001791296.1	hypothetical protein	-
IF710_RS12785 (IF710_12720)	-	2597640..2598095 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
IF710_RS12790 (IF710_12725)	-	2598340..2599101 (-)	762	WP_000323447.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=488719 IF710_RS12760 WP_000143420.1 2593946..2594833(-) (braS) [Staphylococcus aureus strain NAS_AN_109]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=488719 IF710_RS12760 WP_000143420.1 2593946..2594833(-) (braS) [Staphylococcus aureus strain NAS_AN_109]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993