Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KFU68_RS09635 Genome accession   NZ_CP073946
Coordinates   1999896..2000552 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain MB51     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1994896..2005552
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KFU68_RS09605 (KFU68_09515) dcyD 1995775..1996761 (+) 987 WP_257202036.1 D-cysteine desulfhydrase -
  KFU68_RS09610 (KFU68_09520) tcyL 1996776..1997444 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  KFU68_RS09615 (KFU68_09525) tcyN 1997441..1998193 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KFU68_RS09620 (KFU68_09530) sdiA 1998423..1999145 (+) 723 WP_001152713.1 transcriptional regulator SdiA -
  KFU68_RS09625 (KFU68_09535) yecF 1999213..1999437 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  KFU68_RS09630 (KFU68_09540) yecU 1999424..1999600 (-) 177 WP_000590344.1 protein YecU -
  KFU68_RS24290 - 1999638..1999754 (-) 117 Protein_1890 transcriptional regulator -
  KFU68_RS09635 (KFU68_09545) letA 1999896..2000552 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KFU68_RS09640 (KFU68_09550) uvrC 2000549..2002381 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  KFU68_RS09645 (KFU68_09555) pgsA 2002438..2002986 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KFU68_RS09665 (KFU68_09575) yecA 2003636..2004301 (+) 666 WP_128424088.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=488603 KFU68_RS09635 WP_000611335.1 1999896..2000552(+) (letA) [Escherichia coli strain MB51]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=488603 KFU68_RS09635 WP_000611335.1 1999896..2000552(+) (letA) [Escherichia coli strain MB51]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486