Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   IF713_RS02525 Genome accession   NZ_CP062366
Coordinates   450495..451181 (+) Length   228 a.a.
NCBI ID   WP_240021955.1    Uniprot ID   -
Organism   Staphylococcus aureus strain NAS_AN_123     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 445495..456181
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IF713_RS02490 (IF713_02495) yqeH 446022..447122 (+) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -
  IF713_RS02495 (IF713_02500) aroE 447136..447942 (+) 807 WP_000666761.1 shikimate dehydrogenase -
  IF713_RS02500 (IF713_02505) yhbY 447946..448236 (+) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  IF713_RS02505 (IF713_02510) nadD 448239..448808 (+) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  IF713_RS02510 (IF713_02515) yqeK 448798..449382 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  IF713_RS02515 (IF713_02520) rsfS 449383..449736 (+) 354 WP_001088022.1 ribosome silencing factor -
  IF713_RS02520 (IF713_02525) - 449739..450455 (+) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  IF713_RS02525 (IF713_02530) comEA 450495..451181 (+) 687 WP_240021955.1 ComEA family DNA-binding protein Machinery gene
  IF713_RS02530 (IF713_02535) - 451273..451734 (+) 462 WP_000439693.1 ComE operon protein 2 -
  IF713_RS02535 (IF713_02540) comEC 451739..453940 (+) 2202 WP_001548978.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  IF713_RS02540 (IF713_02545) holA 453997..454971 (+) 975 WP_001282562.1 DNA polymerase III subunit delta -
  IF713_RS02545 (IF713_02550) rpsT 455016..455267 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25780.42 Da        Isoelectric Point: 9.0984

>NTDB_id=488563 IF713_RS02525 WP_240021955.1 450495..451181(+) (comEA) [Staphylococcus aureus strain NAS_AN_123]
MVLLYQFLLRYKDFLTQCKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=488563 IF713_RS02525 WP_240021955.1 450495..451181(+) (comEA) [Staphylococcus aureus strain NAS_AN_123]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGTAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

97.797

99.561

0.974
  comEA Staphylococcus aureus N315

96.916

99.561

0.965