Detailed information NTG0488409

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: IF726_RS05185
• Genome accession: NZ_CP062358
• Coordinates: 1045605..1046591 (-)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain NAS_AN_184
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1040605..1051591

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF726_RS05160 (IF726_05155)	-	1040865..1041212 (-)	348	WP_001242103.1	hypothetical protein	-
IF726_RS05165 (IF726_05160)	-	1041398..1041991 (+)	594	WP_000224619.1	CYTH domain-containing protein	-
IF726_RS05170 (IF726_05165)	-	1042095..1042460 (+)	366	WP_000214070.1	truncated hemoglobin YjbI	-
IF726_RS05175 (IF726_05170)	yjbH	1042483..1043289 (+)	807	WP_000896697.1	protease adaptor protein YjbH	-
IF726_RS05180 (IF726_05175)	pepF	1043749..1045557 (-)	1809	WP_240022014.1	oligoendopeptidase F	-
IF726_RS05185 (IF726_05180)	coiA	1045605..1046591 (-)	987	WP_000959282.1	competence protein CoiA family protein	Machinery gene
IF726_RS05190 (IF726_05185)	mecA	1046712..1047431 (-)	720	WP_240022015.1	adaptor protein MecA	-
IF726_RS05195 (IF726_05190)	spxA	1047802..1048197 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
IF726_RS05200 (IF726_05195)	trpS	1048490..1049479 (+)	990	WP_000448934.1	tryptophan--tRNA ligase	-
IF726_RS05205 (IF726_05200)	opp4C	1049521..1050402 (-)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
IF726_RS05210 (IF726_05205)	opp4B	1050414..1051376 (-)	963	WP_000915997.1	oligopeptide ABC transporter permease	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=488409 IF726_RS05185 WP_000959282.1 1045605..1046591(-) (coiA) [Staphylococcus aureus strain NAS_AN_184]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=488409 IF726_RS05185 WP_000959282.1 1045605..1046591(-) (coiA) [Staphylococcus aureus strain NAS_AN_184]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976