NTDB

Overview

Name	coiA	Type	Machinery gene
Locus tag	IF733_RS05205	Genome accession	NZ_CP062352
Coordinates	1050182..1051168 (-)	Length	328 a.a.
NCBI ID	WP_000959282.1	Uniprot ID	A0A7U7EXT8
Organism	Staphylococcus aureus strain NAS_AN_233
Function	require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1045182..1056168

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF733_RS05180 (IF733_05160)	-	1045442..1045789 (-)	348	WP_001242103.1	hypothetical protein	-
IF733_RS05185 (IF733_05165)	-	1045975..1046568 (+)	594	WP_000224619.1	CYTH domain-containing protein	-
IF733_RS05190 (IF733_05170)	-	1046672..1047037 (+)	366	WP_000214070.1	truncated hemoglobin YjbI	-
IF733_RS05195 (IF733_05175)	yjbH	1047060..1047866 (+)	807	WP_000896697.1	protease adaptor protein YjbH	-
IF733_RS05200 (IF733_05180)	pepF	1048326..1050134 (-)	1809	WP_240022454.1	oligoendopeptidase F	-
IF733_RS05205 (IF733_05185)	coiA	1050182..1051168 (-)	987	WP_000959282.1	competence protein CoiA family protein	Machinery gene
IF733_RS05210 (IF733_05190)	mecA	1051289..1052008 (-)	720	WP_001217728.1	adaptor protein MecA	-
IF733_RS05215 (IF733_05195)	spxA	1052379..1052774 (-)	396	WP_000258003.1	transcriptional regulator SpxA	-
IF733_RS05220 (IF733_05200)	trpS	1053068..1054057 (+)	990	WP_000448934.1	tryptophan--tRNA ligase	-
IF733_RS05225 (IF733_05205)	opp4C	1054099..1054980 (-)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
IF733_RS05230 (IF733_05210)	opp4B	1054992..1055954 (-)	963	WP_000915997.1	oligopeptide ABC transporter permease	-

Sequence

Protein

Download Length: 328 a.a. Molecular weight: 38878.55 Da Isoelectric Point: 9.5714

                                >NTDB_id=488284 IF733_RS05205 WP_000959282.1 1050182..1051168(-) (coiA) [Staphylococcus aureus strain NAS_AN_233]

MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV

EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL

HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ

LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR

GNDVQILF

Nucleotide

Download Length: 987 bp

                                >NTDB_id=488284 IF733_RS05205 WP_000959282.1 1050182..1051168(-) (coiA) [Staphylococcus aureus strain NAS_AN_233]

ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT

GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT

GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA

GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA

TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA

ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT

CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA

AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG

CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG

TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG

GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA

AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA

GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

Competence protein CoiA-like family (CoiA_nuc)

(6-308)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A7U7EXT8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976

Detailed information NTG0488284