Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   IF748_RS06245 Genome accession   NZ_CP062336
Coordinates   1293009..1293695 (-) Length   228 a.a.
NCBI ID   WP_001788928.1    Uniprot ID   -
Organism   Staphylococcus aureus strain NAS_NP_161     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1288009..1298695
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IF748_RS06225 (IF748_06205) rpsT 1288923..1289174 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  IF748_RS06230 (IF748_06210) holA 1289219..1290193 (-) 975 WP_001282562.1 DNA polymerase III subunit delta -
  IF748_RS06235 (IF748_06215) comEC 1290250..1292451 (-) 2202 WP_001641560.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  IF748_RS06240 (IF748_06220) - 1292456..1292917 (-) 462 WP_000439693.1 ComE operon protein 2 -
  IF748_RS06245 (IF748_06225) comEA 1293009..1293695 (-) 687 WP_001788928.1 ComEA family DNA-binding protein Machinery gene
  IF748_RS06250 (IF748_06230) - 1293735..1294451 (-) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  IF748_RS06255 (IF748_06235) rsfS 1294454..1294807 (-) 354 WP_001088020.1 ribosome silencing factor -
  IF748_RS06260 (IF748_06240) yqeK 1294808..1295392 (-) 585 WP_001019326.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  IF748_RS06265 (IF748_06245) nadD 1295382..1295951 (-) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  IF748_RS06270 (IF748_06250) yhbY 1295954..1296244 (-) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  IF748_RS06275 (IF748_06255) aroE 1296248..1297054 (-) 807 WP_000666744.1 shikimate dehydrogenase -
  IF748_RS06280 (IF748_06260) yqeH 1297068..1298168 (-) 1101 WP_001280136.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25888.59 Da        Isoelectric Point: 9.6751

>NTDB_id=487954 IF748_RS06245 WP_001788928.1 1293009..1293695(-) (comEA) [Staphylococcus aureus strain NAS_NP_161]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=487954 IF748_RS06245 WP_001788928.1 1293009..1293695(-) (comEA) [Staphylococcus aureus strain NAS_NP_161]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAGTGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAATAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCGAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus N315

100

99.561

0.996
  comEA Staphylococcus aureus MW2

97.357

99.561

0.969