Detailed information NTG0487950

Bioinformatically predicted

Overview

• Name: comGB
• Type: Machinery gene
• Locus tag: IF748_RS06010
• Genome accession: NZ_CP062336
• Coordinates: 1245216..1246286 (-)
• Length: 356 a.a.
• NCBI ID: WP_000776422.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain NAS_NP_161
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1247257..1248903	1245216..1246286	flank	971

Gene organization within MGE regions

Location: 1245216..1248903

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF748_RS06010 (IF748_05990)	comGB	1245216..1246286 (-)	1071	WP_000776422.1	competence type IV pilus assembly protein ComGB	Machinery gene
IF748_RS06015 (IF748_05995)	comGA	1246258..1247232 (-)	975	WP_000697220.1	competence type IV pilus ATPase ComGA	Machinery gene
IF748_RS06020 (IF748_06000)	-	1247257..1248903 (-)	1647	WP_000277718.1	IS1182 family transposase	-

Sequence

Protein

• Length: 356 a.a.
• Molecular weight: 41447.84 Da
• Isoelectric Point: 10.0606

>NTDB_id=487950 IF748_RS06010 WP_000776422.1 1245216..1246286(-) (comGB) [Staphylococcus aureus strain NAS_NP_161]
MKLQWINTFKLHSKKRQLSKAQQIDLLSNLCNLLKYGFTLYQSFQFLNLQMTYKNKQLGTTILSEISNGAPCNQILSLIG
YSDTIVMQVYLAERFGNIIDVLEETVNYMKVNRKSEQRLLKTLQYPLILVSIFIAMIIILNLTVIPQFQQLYTSMNIQLS
SFQKTLSFFITSLPTIIVVMLIIVSMLAIIMKLIYNNLNMLNKINFVMKLPLISGYFQLFKTYFVTNELVLFYKNGITLQ
SIVDVYINHSSDPFRQFLGKYLLTYSEMGYGLPQILEKLKCFKPQLIKFVLQGEKRGKLEVELKLYSQILVKQIEDKAIK
QTQFLQPILFLILGLFIVAIYLVIMLPMFQMMQSIK

Nucleotide

• Length: 1071 bp

>NTDB_id=487950 IF748_RS06010 WP_000776422.1 1245216..1246286(-) (comGB) [Staphylococcus aureus strain NAS_NP_161]
GTGAAACTACAATGGATAAATACATTTAAACTACATTCTAAGAAGCGACAATTAAGTAAGGCCCAACAAATCGACTTACT
TTCAAATTTATGTAATTTGTTGAAATATGGTTTCACTCTGTATCAAAGTTTTCAATTTTTAAATCTTCAAATGACATATA
AAAATAAGCAATTAGGTACCACCATTCTAAGTGAAATTTCAAATGGTGCACCATGCAATCAAATATTATCACTGATAGGT
TATAGCGATACTATCGTCATGCAAGTATATTTGGCAGAAAGATTTGGCAATATTATAGACGTTCTAGAAGAAACCGTAAA
TTATATGAAAGTGAATAGAAAGTCAGAACAACGATTGTTAAAGACACTGCAATACCCCTTAATACTAGTTTCTATCTTTA
TTGCTATGATTATTATATTAAACCTCACAGTAATTCCACAGTTTCAACAATTATATACTTCTATGAATATTCAACTATCT
TCTTTTCAAAAAACATTGTCTTTTTTCATTACCAGCTTACCTACTATAATTGTAGTAATGCTCATAATAGTATCTATGTT
GGCTATTATTATGAAATTAATTTATAACAATTTAAATATGCTCAATAAGATAAACTTTGTGATGAAACTACCGCTAATAT
CAGGCTATTTCCAATTATTTAAAACTTATTTTGTAACTAATGAATTAGTGTTGTTTTATAAAAATGGTATTACACTTCAA
TCAATAGTAGACGTTTATATTAACCATAGTAGTGATCCATTTAGACAGTTTCTAGGTAAATACTTATTAACTTATTCAGA
AATGGGATATGGTTTGCCTCAAATTTTAGAAAAACTAAAATGCTTTAAGCCTCAATTAATTAAGTTTGTGCTACAAGGTG
AAAAGAGAGGGAAGCTAGAAGTAGAACTAAAGTTATATTCGCAAATATTAGTAAAACAAATAGAAGATAAAGCGATAAAA
CAGACTCAGTTTTTACAGCCTATTTTATTTTTGATTTTAGGTTTATTTATTGTCGCAATTTATTTAGTAATTATGTTACC
AATGTTTCAAATGATGCAAAGTATAAAATAA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (227-347)

• Type II secretion system (T2SS), protein F (T2SSF) (27-146)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGB	Staphylococcus aureus MW2	100	100	1
comGB	Staphylococcus aureus N315	100	100	1