Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   IF748_RS06015 Genome accession   NZ_CP062336
Coordinates   1246258..1247232 (-) Length   324 a.a.
NCBI ID   WP_000697220.1    Uniprot ID   W8U5L8
Organism   Staphylococcus aureus strain NAS_NP_161     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1241258..1252232
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IF748_RS05975 (IF748_05955) gcvT 1241759..1242850 (-) 1092 WP_000093348.1 glycine cleavage system aminomethyltransferase GcvT -
  IF748_RS05980 (IF748_05960) - 1243009..1243533 (-) 525 WP_001015123.1 shikimate kinase -
  IF748_RS05985 (IF748_05965) - 1243523..1243669 (-) 147 WP_001789879.1 hypothetical protein -
  IF748_RS05990 (IF748_05970) comGF 1243766..1244263 (-) 498 WP_029642894.1 competence type IV pilus minor pilin ComGF Machinery gene
  IF748_RS05995 (IF748_05975) comGE 1244181..1244480 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  IF748_RS06000 (IF748_05980) comGD 1244467..1244913 (-) 447 WP_001788899.1 competence type IV pilus minor pilin ComGD Machinery gene
  IF748_RS06005 (IF748_05985) comGC 1244891..1245202 (-) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  IF748_RS06010 (IF748_05990) comGB 1245216..1246286 (-) 1071 WP_000776422.1 competence type IV pilus assembly protein ComGB Machinery gene
  IF748_RS06015 (IF748_05995) comGA 1246258..1247232 (-) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  IF748_RS06020 (IF748_06000) - 1247257..1248903 (-) 1647 WP_000277718.1 IS1182 family transposase -
  IF748_RS06025 (IF748_06005) - 1249198..1249821 (-) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  IF748_RS06030 (IF748_06010) - 1249818..1250147 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  IF748_RS06035 (IF748_06015) - 1250147..1251133 (-) 987 WP_000161314.1 ROK family glucokinase -
  IF748_RS06040 (IF748_06020) - 1251130..1251333 (-) 204 WP_000078677.1 YqgQ family protein -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36897.96 Da        Isoelectric Point: 8.8516

>NTDB_id=487951 IF748_RS06015 WP_000697220.1 1246258..1247232(-) (comGA) [Staphylococcus aureus strain NAS_NP_161]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=487951 IF748_RS06015 WP_000697220.1 1246258..1247232(-) (comGA) [Staphylococcus aureus strain NAS_NP_161]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATCGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterProScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

100

100

1
  comGA Staphylococcus aureus N315

100

100

1